C-Peptide EIA Kit

C-Peptide EIA Kit 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	RAB0326	for serum, plasma, culture supernatant and cell lysates C-Peptide EIA Kit for serum, plasma, culture supernatant and cell lysates		1KIT	￥106000	2024-03-01	購入
Sigma-Aldrich Japan	RAB0326	for serum, plasma, culture supernatant and cell lysates C-Peptide EIA Kit for serum, plasma, culture supernatant and cell lysates		1kt	￥79800	2018-12-25	購入

C-Peptide EIA Kit 化学特性,用途語,生産方法

使用

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

一般的な説明

The C-Peptide Enzyme Immunoassay (EIA) Kit is an in vitro quantitative assay for detecting C-Peptide peptide based on the principle of Competitive Enzyme Immunoassay. EIA-CPE-1 only detects C-peptide, not Insulin A or B chain.

Biochem/physiol Actions

C-peptide inhibits endothelial dysfunction under high glucose conditions via inhibition of nuclear factor-κB (NF-κB) pathway. Experimental studies suggest that prolonged dosage of physiological concentration of C-peptide to type 1 diabetes patients minimizes diabetes-induced complications, such as glomerular hypertrophy and mesangial matrix expansion by interrupting transforming growth factor β1 (TGF-β1) and tumor necrosis factor α (TNFα) signaling pathway. C-peptide reduces diabetes-induced glomerular hyperfiltration by contraction of the afferent arteriole, dilation of the efferent arteriole, and by inhibition of tubular reabsorption. C-Peptide also plays a crucial role in renal pathophysiology. C-peptide binds to a cell surface receptor that is likely to be G-protein coupled. This interaction stimulates various cellular functions such as increasing intracellular Ca2+ concentration, enhancing PI3-K (phosphoinositide 3-kinase) activity, increased endothelial nitric oxide synthase (eNOS) transcription, and activation of the Na+/K+ ATPase and mitogen-activated protein kinase (MAPK) signaling pathway.

C-Peptide EIA Kit 上流と下流の製品情報

原材料

準備製品

C-Peptide EIA Kit 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

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• C-Peptide EIA Kit