ポリソルベート20 化学特性,用途語,生産方法
外観
微黄色~黄色の液
定義
本品は、主としてソルビトール(*)及びソルビトール無水物のラウリン酸モノエステルに酸化エチレン約4モルを付加重合したもので、次の化学式で表される。
w+x+y+z:平均4
参照表示名称:ソルビトール
溶解性
水に可溶。エタノール, エーテルに易溶。エタノールに極めて溶けやすく、水に溶ける。
化粧品の成分用途
可溶化剤、乳化剤、洗浄剤、香料
効能
界面活性剤
特長
イオン性界面活性剤と比較して、タンパク質に対する作用が温和です。また可溶化したタンパク質を精製する場合、イオン交換クロマトグラフィや等電点電気泳動を用いることができます
化学的特性
Polysorbate 20 is a mixture of laurate partial esters of sorbitol and sorbitol anhydrides condensed with approximately
20 mole of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It has a faint, characteristic odor and a
warm, somewhat bitter taste.
使用
polysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water.
定義
ChEBI: Polysorbate 20 (Tween 20) is a polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group. It is a surfactant and emulsifier used in cleaners and personal care products.
製造方法
polysorbate 20 is prepared by condensing the partial esters of sorbitol and its anhydrides with ethylene oxide to effect an oxyethylene copolymerization at the free hydroxyl groups.
一般的な説明
Polysorbate 20 is a hydrophilic nonionic surfactant generally used as emulsifiers, dispersing agent and solubilizer.
健康への影響
Polysorbate 20 was a skin irritant in dermatitis patients but was reported not to induce irritant responses when applied to the intact skin of health volunteers. It produced, at worst, minimal irritation in the eyes of rabbits. Only a small number of cases of skin sensitization have been reported in humans, although a moderate to strong sensitizing potential was seen in guinea-pigs treated by intradermal injection.
安全性プロファイル
Moderately toxic by
intravenous route. Mddly toxic by ingestion.
A human skin irritant. When heated to
decomposition it emits acrid smoke and
irritating fumes.
ポリソルベート20 上流と下流の製品情報
原材料
準備製品