(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester

 化学構造式
135053-62-2
CAS番号.
135053-62-2
化学名:
别名:
英語名:
(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester
英語别名:
Methyl 3β-Amino-7α,12α-dihydroxy-5β-cholan-24-oate;(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester;(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester;Cholan-24-oic acid, 3-amino-7,12-dihydroxy-, methyl ester, (3β,5β,7α,12α)-
CBNumber:
CB35830966
化学式:
C25H43NO4
分子量:
421.62
MOL File:
135053-62-2.mol

(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester 物理性質

融点 :
225-230 °C (decomp)
沸点 :
530.9±50.0 °C(Predicted)
比重(密度) :
1.107±0.06 g/cm3(Predicted)
溶解性:
DMSO (Slightly), Methanol (Slightly)
酸解離定数(Pka):
14.67±0.70(Predicted)
外見 :
Solid
色:
White to Off-White

安全性情報

(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester 価格

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(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester 化学特性,用途語,生産方法

使用

Methyl 3β-Amino-7α,12α-dihydroxy-5β-cholan-24-oate is a reagent used in the formation of dimers carrying four carboxy groups as tetracarboxylic surfactants. Also, it is an intermediate used in the synthesis of Aramchol (A765150), which is a fatty acid conjugate that exhibits?hypocholesterolemic effects and Studies have shown that aramchol?suppresses the activity of?stearoyl-CoA desaturase (SCD), which leads to reduction of obesity, fatty liver and insulin resistance.

(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester 上流と下流の製品情報

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(3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester 生産企業

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  • 135053-62-2
  • Methyl 3β-Amino-7α,12α-dihydroxy-5β-cholan-24-oate
  • Cholan-24-oic acid, 3-amino-7,12-dihydroxy-, methyl ester, (3β,5β,7α,12α)-
  • (3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester
  • (3β,5β,7α,12α)-3-amino-7,12-dihydroxycholan-24-oic acid methyl ester
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