キモスタチン 化学特性,用途語,生産方法
説明
Chymostatin is a bioactive peptide of microbial origin that acts as a protease inhibitor with selectivity for chymotryptase-
like serine proteases. It potently inhibits chymotrypsin and chymase (K
i = 9.36 and 13.1 nM, respectively) while less effectively blocking the activity of cathepsins, papain, and leukocyte elastase. It is without effect on trypsin, thrombin, plasmin, pepsin, and kallikrein.
使用
Chymostatin is a specific inhibitor of α-, β-, γ-, and δ-chymotrypsin.
一般的な説明
Chymostatin is a mixture of three components, A, B, and C. The component A being
N-[((S)-1-carboxy-2-phenylethyl)-carbamoyl]-α-[2-iminohexahydro-4(S)-pyrimidyl]-L-glycyl-L-leucyl-phenylalaninal. The other two components B and C differ in that the L-leucyl residue is substituted by L-valine and L-isoleucine, respectively.
キモスタチン 上流と下流の製品情報
原材料
準備製品