13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 化学特性,用途語,生産方法
説明
13,14-
dihydro-
15-
keto Prostaglandin E
1 (PGE
1) is a metabolite of PGE
1 with much reduced biological activity. Steady state plasma concentrations are about 10 pg/ml. 13,14-
dihydro-
15-
keto PGE
1 is a weak inhibitor of ADP-
induced platelet aggregation in human PRP and washed platelets with IC
50 values of 54 and 200 μM, respectively, compared to PGE
1 which has an IC
50 of 40 nM.
使用
15-Keto Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and has been shown to induce arterial thromboresistance in experimental animals and in man, but with several magnitudes higher concentrations than Prostaglandin E1. 15-Keto Prostaglandin E0 is also used as the active ingredient in compositions used for the treatment of external secretion disorders.
13,14-DIHYDRO-15-KETO PROSTAGLANDIN E1 上流と下流の製品情報
原材料
準備製品