PAF-AH ヒト
PAF-AH ヒト 物理性質
- 貯蔵温度 :
- -20°C
- 外見 :
- 凍結乾燥
- 色:
- 白い
PAF-AH ヒト 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
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PAF-AH ヒト 化学特性,用途語,生産方法
使用
Antiallergenic;
antiasthmatic (PAF antagonist [PAF acetylhydrolasemphor.].
一般的な説明
Recombinant PAF-AH is a 420 amino acid glycoprotein which migrates with an apparent molecular mass of 47-55kDa by SDS-PAGE analysis.
Biochem/physiol Actions
Platelet Activating Factor (PAF) is a biologically active phospholipid, which exerts primarily proinflammatory activities by specifically signaling through G-protein-coupled receptors on platelets, neutrophils, and monocytes. Platelet activating factor acetylhydrolase (PAF-AH) is a secreted protein that mediates PAF activity by specifically catalyzing hydrolysis of the "sn2" ester bond, resulting in the conversion of PAF to the biologically inactive lyso-PAF. PAF-AH can also interact with LDL (low density lipoprotein) particles to induce the hydrolysis of LDL associated, oxidized phospholipids, generating lysophosphatidylcholine (lyso-PC) and other lysophospholipids. High levels of PAF-AH in plasma can be an indication of resistant hypertension. Polymorphism in PAF-AH gene at A379V might be linked with ischemic stroke susceptibility.
PAF-AH ヒト 上流と下流の製品情報
原材料
準備製品
PAF-AH ヒト 生産企業
Global( 5)Suppliers
- 208576-22-1
- 2-Acetyl-1-alkyl-sn-glycero-3-phosphocholine deacetylase-(6-400)-peptide (human)
- Deacetylase, 1-alkyl-2-acetyllecithin (human)
- Epafipase
- Epafipase [usan:inn]
- Paf acetylhydrolase
- Pafase
- Rpaf-ah
- 2-acetyl-1-alkylglycerophosphocholine esterase
- LDL-associated phospholipase A2
- PAF 2-acylhydrolase
- PAF-AH human
- PAF-AH ヒト