2-((3-(1,3-ジオキソ-(1H)ベンゾ[DE]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸

2-((3-(1,3-ジオキソ-(1H)ベンゾ[DE]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸 価格 もっと(6)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TOC4779	GRI 977143	325850-81-5	10mg	￥74000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TOC4779	GRI 977143	325850-81-5	50mg	￥306000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCD486350	2-((3-(1,3-ジオキソ-(1H)ベンゾ[de]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸 2-((3-(1,3-Dioxo-(1H)benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoic Acid	325850-81-5	100mg	￥451600	2023-06-01	購入
Sigma-Aldrich Japan	SML0544	≥98% (HPLC) GRI977143 ≥98% (HPLC)	325850-81-5	5mg	￥18600	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCD486350	2-((3-(1,3-ジオキソ-(1H)ベンゾ[de]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸 2-((3-(1,3-Dioxo-(1H)benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoic Acid	325850-81-5	10mg	￥56900	2023-06-01	購入

2-((3-(1,3-ジオキソ-(1H)ベンゾ[DE]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸 化学特性,用途語,生産方法

説明

GRI-977143 is an agonist of G protein-coupled lysophosphatidic acid receptor 2 (LPA₂) with an EC₅₀ value of 3.3 μM in LPA₂-transfected RH7777 cells. It is selective for LPA₂, having no activity at LPA₁, LPA₃, LPA₄, and LPA₅ at concentrations up to 10 μM. GRI-977143 increases growth and reduces caspase-3 and -7 activation in LPA₂-transduced MEF fibroblasts. It increases MM1 rat hepatoma cell invasion and inhibits apoptosis of IEC-6 cells induced by TNF-α, doxorubicin , or serum withdrawal. GRI-977143 also rescues apoptotic cells from γ-irradiation-induced injury in vitro and in vivo.

使用

2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid is used as a non-lipid agonist of LPA2. LPA (Lipoprotein Associated Phospholipase A2/A3 are important factors in prediction of diseases involving fatty acids such as coronary heart disea se or atherosclerosis.

2-((3-(1,3-ジオキソ-(1H)ベンゾ[DE]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸 上流と下流の製品情報

原材料

準備製品

2-((3-(1,3-ジオキソ-(1H)ベンゾ[DE]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Shanghai Yolne Chemical Co., Ltd.	021-62960152	934678158@qq.com	China	9906	55
AdooQ BioScience, LLC	+1 (866) 930-6790	info@adooq.com	United States	2784	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Pharmacodia (Beijing) Co.,Ltd	+86-400-851-9921	sales@pharmacodia.com	China	2317	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	4192	55

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• 325850-81-5
• 2-((3-(1,3-Dioxo-(1H)benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoic Acid
• 2-[[3-(1,3-Dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-benzoic acid
• GRI977143
• 2-[3-(1,3-Dioxo-1H,3H-benzo[de]isoquinolin-2-yl)-propylsulfanyl]-benzoic acid
• GRI977143; GRI-977143
• Benzoic acid, 2-[[3-(1,3-dioxo-1H-benz[de]isoquinolin-2(3H)-yl)propyl]thio]-
• 2-((3-(1,3-Dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)propyl)thio)benzoic acid , GRI977143
• 2-((3-(1,3-ジオキソ-(1H)ベンゾ[DE]イソキノリン-2(3H)-イル)プロピル)チオ)安息香酸
• 2-[(3-{2,4-ジオキソ-3-アザトリシクロ[7.3.1.05,13]トリデカ-1(13),5,7,9,11-ペンタエン-3-イル}プロピル)スルファニル]安息香酸
• 2-[[3-[1,3-ジオキソ-1H-ベンゾ[de]イソキノリン-2(3H)-イル]プロピル]チオ]安息香酸