4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE 化学特性,用途語,生産方法
説明
CAY10398 is an inhibitor of histone deacetylase (HDAC1) with an IC
50 value of 10 μM. Similar potency is observed with trapoxin A and B, whereas trichostatin A is more potent inhibitor of the enzyme. Trichostatin A also selectively inhibits the removal of acetyl groups from the amino-
terminal lysine residues of core histones, which modulates the access of transcription factors to the underlying genomic DNA. However, trichostatin A is much more expensive than CAY10398. CAY10398 thus represents a selective and cost-
effective compound for the inhibition of HDAC.
使用
A histone deacetylase (HDAC1) inhibitor
4-(DIMETHYLAMINO)-N-[6-(HYDROXYAMINO)-6-OXOHEXYL]-BENZAMIDE 上流と下流の製品情報
原材料
準備製品