ANTI-GLUTAMATE RECEPTOR 7, METABOTROPIC 化学特性,用途語,生産方法
使用
Anti-Glutamate Receptor 7, Metabotropic antibody produced in rabbit is suitable for immunohistochemistry using formalin-fixed, paraffin-embedded sections of human brain, neurons.
一般的な説明
The metabotropic glutamate receptors consist of eight subtypes (mGluR1-8) divided into three groups (I-III). Glutamate is the main excitatory neurotransmitter in the brain. It acts on ligand-gated receptor channels, termed NMDA, AMPA and kainate receptors, involved in the fast excitatory synaptic transmission. Glutamate also regulates ion channels and enzymes producing second messengers via specific receptors coupled to G-proteins, called metabotropic glutamate receptors.
Biochem/physiol Actions
Glutamate Receptor 7 belongs to group III and inhibits adenyl cyclase. The role of the metabotropic receptors in pain and pathology is being studied for therapeutic potential. Activation of Group III receptors has been shown to be neuroprotective. Glutamate receptors are important mediators of excitatory amino acid neurotransmission.
ANTI-GLUTAMATE RECEPTOR 7, METABOTROPIC 上流と下流の製品情報
原材料
準備製品