ANTI-SYNAPTOPODIN (SE-19)

ANTI-SYNAPTOPODIN (SE-19) 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

ANTI-SYNAPTOPODIN (SE-19) 化学特性,用途語,生産方法

使用

Anti-Synaptopodin (SE-19) antibody produced in rabbit has been used in:

• immunofluorescence microscopy
• immunohistochemistry
• western blotting

一般的な説明

Synaptopodin is a proline-rich, actin-associated protein (100 kDa) is present in the post-synaptic density (PSD) in actin cytoskeleton. It is also present in the dendritic spines and differentiated podocytes. Synaptopodin contains a high amount of proline residues (~20%), which are evenly distributed along the protein sequence, thus virtually excluding the formation of globular domains. In particular, synaptopodin does not contain functional domains found in receptor clustering PSD proteins. Sequence comparison between human and mouse synaptopodin shows 84% identity. The exclusive site of synaptopodin expression in the telencephalon is restricted to specific areas of high synaptic plasticity, i.e. in the perykaria of the olfactory bulb, striatum, and hippocampus.

Biochem/physiol Actions

Synaptopodin is thought to play an important role in synaptic plasticity and is associated in the modulation of motility of actin in neuronal dendritic spines. The association of synaptopodin with the specialized actin system of renal podocyte foot processes suggests that it may play a role in actin cytoskeleton dynamics of these cellular extensions. Synaptopodin has been found to interact with α-actinin-4 and the tight junction protein Membrane-associated guanylate kinase inverted 1 (MAGI-1) in Madin-Darby Canine Kidney (MDCK) cells.

ANTI-SYNAPTOPODIN (SE-19) 上流と下流の製品情報

原材料

準備製品

ANTI-SYNAPTOPODIN (SE-19) 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80

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• ANTI-SYNAPTOPODIN (SE-19)
• Anti-Synaptopodin (SE-19) antibody produced in rabbit