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(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID

化学構造式
909400-43-7
CAS番号.
909400-43-7
化学名:
别名:
英語名:
(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
英語别名:
CL-HIBO;ClHIBO,Cl HIBO;4-Chlorohomoibotenic acid;2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID;5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-;(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
CBNumber:
CB4691192
化学式:
C6H7ClN2O4
分子量:
206.58
MOL File:
Mol file

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID 物理性質

比重(密度) :
1.66±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at RT
酸解離定数(Pka):
2.26±0.10(Predicted)
外見 :
Powder
水溶解度 :
Soluble to 20 mM in water

安全性情報

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TOC1673
Cl-HIBO 		909400-43-7 10mg ￥83000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01TOC1673
Cl-HIBO 		909400-43-7 50mg ￥344000 2024-03-01 購入

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID 化学特性,用途語,生産方法

使用

The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA receptor), a heterotetrameric transmembrane receptor, is found in various areas of the brain and mediates fast synaptic transmission in the central nervous system (1). Cl-HIBO (chloro-homoibotenic acid) is a subtype selective AMPA receptor agonist (2).

生物活性

Subtype-selective and strongly desensitising AMPA receptor agonist; selective for GluR1 and GluR2 subunit-containing receptors (EC 50 values are 4.7, 1.7, 2700 and 1300 μ M for rat recombinant homomeric GluR1, 2, 3 and 4 receptors respectively).

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID 上流と下流の製品情報

原材料

準備製品

(RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID 生産企業

Global( 22)Suppliers
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
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EMMX Biotechnology LLC 888-539-0666
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BOC Sciences --
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MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8141 58
JinOu Biomedical (Nanjing) Co., Ltd. 13000000000
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TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 23960 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581
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ApexBio Technology --
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  • 909400-43-7
  • 2-AMINO-3-(4-CHLORO-3-HYDROXYISOXAZOL-5-YL)PROPANOIC ACID
  • CL-HIBO
  • (RS)-2-AMINO-3-(4-CHLORO-3-HYDROXY-5-ISOXAZOLYL)PROPIONIC ACID
  • 4-Chlorohomoibotenic acid
  • 5-Isoxazolepropanoic acid, α-amino-4-chloro-2,3-dihydro-3-oxo-
  • ClHIBO,Cl HIBO
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