ヒドロキシプロピルデンプンリン酸 化学特性,用途語,生産方法
定義
本品は、リン酸(*)とデンプンとのジエステルのヒドロキシプロピルエーテルである。参照表示名称：リン酸
化粧品の成分用途
親水性増粘剤、増量剤
化学的特性
Hydroxypropyl starch occurs as a free-flowing white to off-white
coarse powder.
調製方法
Hydroxypropyl starch is produced industrially from natural starch,
using propylene oxide as the modifying reagent in the presence of
alkali, adding hydroxypropyl (CH(OH)CH2CH3) groups at the
OH positions by an ether linkage.
応用例（製薬）
Hydroxypropyl starch is a modified starch and has been used in
combination with carrageenan in the production of soft capsules.
Hydroxypropyl starch has been used experimentally in hydrophilic
matrices, where it was shown to be an effective matrix for tablets
designed for controlled-release drug delivery systems.It has also
been used experimentally in the production of hydrophilic matrices
by direct compression.
It is used in antiseptics and is used widely in cosmetics. It is also
used analytically as a bioseparation aqueous-phase-forming polymer.
安全性
Hydroxypropyl starch is widely used in cosmetics and food
products. It is also used in oral pharmaceutical formulations. The
WHO has set an acceptable daily intake for hydroxypropyl starch
at ‘not limited’ since it was well tolerated on oral consumption.
LD50 (rat, oral): 0.218 g/kg
貯蔵
Hydroxypropyl starch is stable at high humidity and is considered
to be inert under normal conditions. It is stable in emulsion systems
at pH 3–9.
規制状況(Regulatory Status)
GRAS listed. Accepted for use as a food additive in Europe.
ヒドロキシプロピルデンプンリン酸 上流と下流の製品情報
原材料
準備製品