デキスラゾキサン塩酸塩
デキスラゾキサン塩酸塩 物理性質
- 貯蔵温度 :
- Inert atmosphere,Room Temperature
- 溶解性:
- ≥ 15.24mg/mL in DMSO
- 外見 :
- Solid
- 色:
- White to off-white
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
デキスラゾキサン塩酸塩 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
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デキスラゾキサン塩酸塩 化学特性,用途語,生産方法
効能
解毒薬
作用機序
As a derivative of EDTA, dexrazoxane chelates iron and thus reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals. The exact chelation mechanism is unknown, but it has been postulated that dexrazoxane can be converted into ring-opened form intracellularly and interfere with iron-mediated free radical generation that is in part thought to be responsible for anthryacycline induced cardiomyopathy. It was speculated that dexrazoxane could be used for further investigation to synthesize new antimalarial drugs.
使用
Dexrazoxane is used to reduce the risk and severity of heart damage caused by doxorubicin treatment and similar cancer chemotherapy medications. Heart damage limits the length of time you can be treated with doxorubicin. Dexrazoxane allows you to continue doxorubicin treatment for longer. When used for this purpose, dexrazoxane treatment is usually started after you have received several doses of doxorubicin. It is usually not given with the first doses of doxorubicin since doing so may reduce the effectiveness of doxorubicin.
デキスラゾキサン塩酸塩 上流と下流の製品情報
原材料
準備製品
デキスラゾキサン塩酸塩 生産企業
Global( 110)Suppliers
デキスラゾキサン塩酸塩 スペクトルデータ(1HNMR)
149003-01-0(デキスラゾキサン塩酸塩)キーワード:
- 149003-01-0
- Dexrazoxane hydrochloride
- (S)-4,4'-(1-Methyl-1,2-ethanediyl)bis-2,6-piperazinedione hydrochloride
- Dexrazoxane HCL
- ICRF-187 hydrochloride
- Dexrazoxane HCl (ICRF-187, ADR-529)
- 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-2,6-piperazinedione, hydrochloride (1:1)
- ICRF-187 (ADR-529) HCl
- exrazoxanehydrochloride
- Dexrazoxane xHCl (ICRF-187)
- (S)-4,4'-(Propane-1,2-diyl)bis(piperazine-2,6-dione) hydrochloride
- Dexrazoxane hydrochloride (ICRF-187, ADR-529)
- (S)-4,4'-(1-Methyl-1,2-ethanediyl)bis-2,6-piperazinedione hydrochloride(1:)
- ADR-529 Hydrochloride
- Cardioxane hydrochloride
- Right rezzo hydrochloride
- Dexrazoxane HCl (ICRF-187)
- デキスラゾキサン塩酸塩