20,22-dihydroxycholesterol
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- CAS番号.
- 596-94-1
- 化学名:
- 别名:
- 英語名:
- 20,22-dihydroxycholesterol
- 英語别名:
- Oxy-16;Oxy-16, Oxysterol;20,22-dihydroxycholesterol;ISBSSBGEYIBVTO-RCXKVKFCSA-N;(3β,22R)-Dihydroxy Cholesterol;(3β,22R)-Dihydroxy Cholesterol;20α,22(R)-Dihydroxycholesterol;(20R,22R)-Dihydroxycholesterol;(22R)-5-Cholesten-3β,20α,22-triol;(22R)-Cholest-5-ene-3β,20,22-triol
- CBNumber:
- CB61372988
- 化学式:
- C27H46O3
- 分子量:
- 418.65
- MOL File:
- 596-94-1.mol
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20,22-dihydroxycholesterol 物理性質
- 融点 :
- 183 °C(Solv: ethyl acetate (141-78-6))
- 沸点 :
- 553.5±25.0 °C(Predicted)
- 比重(密度) :
- 1.08±0.1 g/cm3(Predicted)
- 貯蔵温度 :
- Store at -20°C
- 溶解性:
- ≤10mg/ml in ethanol;1.5mg/ml in DMSO;1.5mg/ml in dimethyl formamide
- 外見 :
- crystalline solid
- 酸解離定数(Pka):
- 14.42±0.29(Predicted)
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
20,22-dihydroxycholesterol 価格
もっと(2)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
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W01TRCD452465 |
(3β,22R)-Dihydroxy Cholesterol |
596-94-1 |
2.5mg |
￥56900 |
2023-06-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCD452465 |
(3β,22R)-Dihydroxy Cholesterol |
596-94-1 |
25mg |
￥451600 |
2023-06-01 |
購入 |
20,22-dihydroxycholesterol 化学特性,用途語,生産方法
説明
Naturally occurring oxysterols are products of cholesterol oxidation that can stimulate the hedgehog (Hh) signaling pathway in target cells associated with cardiovascular disease and with bone formation. Depending on the target cell, activation of Hh signaling can modulate inflammatory responses to additional atherogenic factors such as lesion-
producing macrophages or enable osteoblast differentiation. Oxy-
16 is a synthetic oxysterol compound that may function as an antagonist of hedgehog activity. Published data regarding its efficacy remains forthcoming.
使用
A metabolite of Cholesterol (C432501). Cholesterol is metabolized to Pregnenolone by way of 22R-hydroxycholesterol and 20R,22R-dihydroxycholesterol by P 450scc.
定義
ChEBI: An oxysterol that is cholesterol substituted by hydroxy groups at positions 20 and 22 (the 20R,22R-stereoisomer).
20,22-dihydroxycholesterol 上流と下流の製品情報
原材料
準備製品
20,22-dihydroxycholesterol 生産企業
Global( 32)Suppliers
- 596-94-1
- 20,22-dihydroxycholesterol
- Oxy-16
- (20R,22R)-Dihydroxycholesterol
- (22R)-5-Cholesten-3β,20α,22-triol
- (22R)-Cholest-5-ene-3β,20,22-triol
- (3β,22R)-Cholest-5-ene-3,20,22-triol
- 20α,22(R)-Dihydroxycholesterol
- (3β,22R)-Dihydroxy Cholesterol
- ISBSSBGEYIBVTO-RCXKVKFCSA-N
- Cholest-5-ene-3,20,22-triol, (3β,22R)-
- (3β,22R)-Dihydroxy Cholesterol
- Oxy-16, Oxysterol