リンシチニブ

リンシチニブ 価格 もっと(5)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01COBQJ-3096	Osi-906	867160-71-2	100mg	￥130000	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01COBQJ-3096	Osi-906	867160-71-2	500mg	￥1090800	2020-09-21	購入
富士フイルム和光純薬株式会社(wako)	W01FLC051063	リンシチニブ Linsitinib	867160-71-2	500mg	￥1090800	2020-09-21	購入
富士フイルム和光純薬株式会社(wako)	W01FLC051063	リンシチニブ Linsitinib	867160-71-2	25mg	￥198700	2018-12-26	購入
富士フイルム和光純薬株式会社(wako)	W01FLC051063	リンシチニブ Linsitinib	867160-71-2	300mg	￥400000	2018-12-26	購入

リンシチニブ 化学特性,用途語,生産方法

効能

抗悪性腫瘍薬, インスリン様増殖因子受容体拮抗薬

説明

The binding of insulin-like growth factor 1 (IGF-1) to the IGF-1 receptor (IGF-1R) promotes cell growth while inhibiting apoptotic pathways. Overexpression of IGF-1R is found in certain solid tumors and hematologic neoplasias. However, insulin receptor (InsR) signaling can compensate for IGF-1R inhibition. Linsitinib is a dual inhibitor of IGF-1R and InsR kinases (IC₅₀s = 35 and 75 nM, respectively). It also inhibits InsR-related receptor (IC₅₀ = 75 nM) but is without effect (IC₅₀ > 10 μM) against a large panel of other kinases. Linsitinib inhibits proliferation of a variety of tumor cell lines in vitro and has antitumor efficacy in an IGF-1R-driven xenograft mouse model when administered orally. A rapid, non-invasive method to predict the pharmacodynamic response to linsitinib has been reported.

リンシチニブ 上流と下流の製品情報

原材料

準備製品

リンシチニブ 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29798	60
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9337	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32760	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Changzhou PBpharmaceutical R&D Co.,Ltd	0519-83990708	info@pbpharm.com	CHINA	498	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49391	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29826	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	25655	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10522	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58

867160-71-2(リンシチニブ)キーワード:

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• 867160-71-2
• cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol
• Linsitinib
• OSI-906 Linsitinib
• Cyclobutanol, 3-[8-aMino-1-(2-phenyl-7-quinolinyl)iMidazo[1,5-a]pyrazin-3-yl]-1-Methyl-, cis-
• OSI 906AA
• (1S,3r)-3-((S)-8-aMino-1-(2-phenylquinolin-7-yl)-2,3-dihydroiMidazo[1,5-a]pyrazin-3-yl)-1-Methylcyclobutanol
• (1s,3r)-3-[4-aMino-3-(2-phenylquinolin-7-yl)iMidazo[1,5-a]pyrazin-1-yl]-1-Methylcyclobutan-1-ol
• Linsitinib, Free Base
• Linsitinib(OSI906)
• (1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutanol
• cis-3-[8-Amino-1-(2-phenyl-7-quinolinyl)imidazo[1,5-a]pyrazin-3-yl]-1-methylcyclobutanol Linsitinib(OSI906)
• 3-(8-Amino-1-(2-phenylquinolin-7-yl)-2,3-dihydro-imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobuta
• LINSITINIB;OSI 906; OSI906
• CS-190
• OSI 906;OSI906
• 3-[8-AMINO-1-(2-PHENYLQUINOLIN-7-YL)IMIDAZO[1,5-A]PYRAZIN-3-YL]-1-METHYLCYCLOBUTAN-1-OL
• (1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol
• Linsitinib USP/EP/BP
• OSI-906
• Cis-3-(8-Amino-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-3-yl)-1-methylcyclobutan-1-ol
• リンシチニブ
• 3α-[8-アミノ-1-(2-フェニルキノリン-7-イル)イミダゾ[1,5-a]ピラジン-3-イル]-1-メチルシクロブタン-1α-オール
• (1s,3r)-3-[8-アミノ-1-(2-フェニルキノリン-7-イル)イミダゾ[1,5-a]ピラジン-3-イル]-1-メチルシクロブタン-1-オール