VEGFR2 Kinase Inhibitor II

VEGFR2 Kinase Inhibitor II 価格

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VEGFR2 Kinase Inhibitor II 化学特性,用途語,生産方法

一般的な説明

A cell-permeable and reversible indolin-2-one class of receptor tyrosine kinase (RTK) inhibitor [IC₅₀ = 70 nM for VEGF-R2 (KDR/Flk-1), 920 nM for PDGF-Rβ, 4.92 μM for p60^c-src, and 13.3 μM for FGF-R1]. The inhibition is suggested to be competitive with respective to ATP. Also inhibits VEGF-induced (IC₅₀ = 110 nM) and PDGF-induced (IC₅₀ = 2.01 μM) cell proliferation in umbilical vein endothelial cells (HUVEC). Does not exhibit any inhibitory effect on EGF-R kinase activity (IC₅₀ >100 μM).

Biochem/physiol Actions

Cell permeable: yes

VEGFR2 Kinase Inhibitor II 上流と下流の製品情報

原材料

準備製品

VEGFR2 Kinase Inhibitor II 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
BOC Sciences	16314854226	info@bocsci.com	United States	9926	65
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Jinan ponder chemical co. LTD	0531-0000	thinklifescience@163.com	China	19690	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	8740	58

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• 288144-20-7
• VEGFR2 Kinase Inhibitor II
• (3Z)-5-bromo-3-(4,5,6,7-tetrahydro-1H-indol-2-ylmethylidene)-1H-indol-2-one
• VEGFR2 Kinase Inhibitor II - CAS 288144-20-7 - Calbiochem
• 2H-Indol-2-one, 5-bromo-1,3-dihydro-3-[(4,5,6,7-tetrahydro-1H-indol-2-yl)methylene]-, (3Z)-
• VEGFR2 Kinase Inhibitor II,VEGFR-2 Kinase Inhibitor II