(S,S)-ICG001

(S,S)-ICG001 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01TRCI163800	(S,S)-ICG001 (S,S)-ICG 001	847591-62-2	5mg	￥55300	2023-06-01	購入
富士フイルム和光純薬株式会社(wako)	W01TRCI163800	(S,S)-ICG001 (S,S)-ICG 001	847591-62-2	50mg	￥431200	2023-06-01	購入

(S,S)-ICG001 化学特性,用途語,生産方法

使用

(S,S)-ICG 001 is a β-turn peptidomimetic molecule inhibitor of β-catenin-Tcf-mediated transcription.

一般的な説明

A cell-permeable pyrazinopyrimidinecarboxamide that competes against β-catenin for CBP (CREB-binding protein) binding and selectively prevents CBP- but not p300-, dependent TCF/β-catenin transcriptional regulations both in cultures in vitro (5 to 25 μM) and in mice in vivo (5 mg/kg/day via osmotic pump infusion), while not affecting CBP-dependent transcriptional activities mediated by the AP-1 or CRE complex. Shown to reactivate p300//TCF/β-catenin-mediated neuronal differentiation upon NGF stimulation in PS-1 L286V mutant-expressing PC-12 cultures and be efficacious in alleviating bleomycin- (0,08 units/50 μL/mouse; administered intranasally; Cat. No. 203401) induced pulmonary fibrosis in mice.

Biochem/physiol Actions

Cell permeable: yes

(S,S)-ICG001 上流と下流の製品情報

原材料

準備製品

(S,S)-ICG001 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32951	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	965	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49374	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29814	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32072	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Henan Alfa Chemical Co., Ltd	+86-18339805032; +8618339805032	alfa4@alfachem.cn	China	13227	58
PT CHEM GROUP LIMITED		peter68@ptchemgroup.com	China	35425	58
Hu Bei Jiutian Bio-medical Technology CO.,Ltd	027-88013699 17354350817	Ryan@jiutian-bio.com	China	6000	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58

847591-62-2((S,S)-ICG001)キーワード:

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• 847591-62-2
• ICG-001
• 2H-Pyrazino[1,2-a]pyriMidine-1(6H)-carboxaMide, hexahydro-6-[(4-hydroxyphenyl)Methyl]-8-(1-naphthalenylMethyl)-4,7-dioxo-N-(phenylMethyl)-, (6S,9aS)-
• ICG-1
• (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide
• ICG-001/ICG001
• (6S,9aS)-Hexahydro-6-[(4-hydroxyphenyl)methyl]-8-(1-naphthalenylmethyl)-4,7-dioxo-N-(phenylmethyl)-2H-pyrazino[1,2-a]pyrimidine-1(6H)-carboxamide ICG001
• ICG 001, >=98%
• ICG-001;ICG 001;ICG001
• (6S,9AS)-6-(4-hydroxybenzyl)-N-benzyl-8-(naphthalen-1-ylmethyl)-4,7-dioxo-hexahydro-2H-pyrazin
• ICG 001 isomer.
• ICG001 isomer
• ICG-001 isomer
• CS-1928
• β-Catenin/Tcf Inhibitor VI, ICG-001 - CAS 847591-62-2 - Calbiochem
• PRI-724 isomer
• (S,S)-ICG001
• (6S,9aS)-N-ベンジル-6-[(4-ヒドロキシフェニル)メチル]-8-[(ナフタレン-1-イル)メチル]-4,7-ジオキソ-オクタヒドロ-1H-ピラジノ[1,2-a]ピリミジン-1-カルボキサミド
• (9aα)-オクタヒドロ-N-ベンジル-6β-(4-ヒドロキシベンジル)-4,7-ジオキソ-8-(1-ナフチルメチル)-2H-ピラジノ[1,2-a]ピリミジン-1-カルボアミド
• ICG-001
• (6S,9aS)-1,3,4,7,8,9,9a-ヘプタヒドロ-6-(4-ヒドロキシベンジル)-8-(ナフタレン-1-イルメチル)-4,7-ジオキソ-N-フェニルメチル-2H-ピラジノ[1,2-a]ピリミジン-1(6H)-カルボキサミド