Chinese english Germany Korea

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-

化学構造式
168960-18-7
CAS番号.
168960-18-7
化学名:
别名:
英語名:
CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-
英語别名:
TERT-BUTYL (1R,4S)-4-(HYDROXYMETHYL)CYCLOPENT-2-ENYLCARBAMATE;tert-Butyl ((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate;TERT-BUTYL CIS-[4(S)-(HYDROXYMETHYL)CYCLOPENT-2-EN-1(R)-YL]CARBAMATE;Carbamic acid, [(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1-;(1R,4S)-N-(tert-Butyloxycarbonyl)-1-amino-4-(hydroxymethyl)-2-cyclopentene;1-((1R,4S)-4-(Hydroxymethyl)cyclopent-2-en-1-yl)-2-methylpropan-2-yl carbamate;N-[(1R,4S)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]-carbamic Acid 1,1-Dimethylethyl Ester;Carbamic acid, N-[(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1-dimethylethyl ester;CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-
CBNumber:
CB6326249
化学式:
C11H19NO3
分子量:
213.27
MOL File:
168960-18-7.mol

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- 物理性質

沸点 :
338.8±31.0 °C(Predicted)
比重(密度) :
1.09±0.1 g/cm3(Predicted)
貯蔵温度 :
2-8°C
溶解性:
DMSO;メタノール
酸解離定数(Pka):
12.06±0.40(Predicted)
外見 :
油
色:
黄色
安全性情報
  • リスクと安全性に関する声明
  • 危険有害性情報のコード(GHS)
絵表示（GHS）
注意喚起語
危険有害性情報
コード 危険有害性情報 危険有害性クラス 区分 注意喚起語 シンボル P コード
H412 長期的影響により水生生物に有害 水生環境有害性、慢性毒性 3 P273, P501
注意書き
P273 環境への放出を避けること。
P501 内容物/容器を．．．に廃棄すること。

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- 価格 もっと(7)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01COBQP-7124
tert-Butyl ((1r,4s)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate 		168960-18-7 100mg ￥107500 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQP-7124
tert-Butyl ((1r,4s)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate 		168960-18-7 250mg ￥215000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQP-7124
tert-Butyl ((1r,4s)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate 		168960-18-7 1g ￥540000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01COBQP-7124
tert-Butyl ((1r,4s)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate 		168960-18-7 5g ￥1800000 2024-03-01 購入
富士フイルム和光純薬株式会社(wako) W01FLC437451
1-((1R,4S)-4-(Hydroxymethyl)cyclopent-2-en-1-yl)-2-methylpropan-2-yl carbamate 		168960-18-7 250mg ￥120000 2021-03-23 購入

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- 化学特性,用途語,生産方法

使用

N-?[(1R,?4S)?-?4-?(Hydroxymethyl)?-?2-?cyclopenten-?1-?yl]?-carbamic Acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing ent-Abacavir (Abacavir EP Impurity A) (A105015), an enatiomer of Abacavir (A105000). Abacavir is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- 上流と下流の製品情報

原材料

準備製品

(1S,4R)-4-アミノ-2-シクロペンテン-1-メタノール

CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)- 生産企業

Global( 19)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63711 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52927 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131980 58
DKMbiochem.Co. Ltd 15901859516
 sales@DKMbiochem.com China 344 58
Aikon International Limited 025-58859352 18068836627
 sales01@aikonchem.com China 15085 58
Shanghai Jizhi Biochemical Technology Co. Ltd. 400-400-400-9004166 18616739031
 3007523370@qq.com China 52712 58
Henan Pumei Jihua Pharmaceutical Technology Co., Ltd. 037188900765 18037465274
 enyawanglei@sina.cn China 13648 58
Nanjing Dalton chemical technology company limited 15051832550
 dongxueping1984@126.com China 160 58
Energy Chemical 021-58432009 400-005-6266
 marketing@energy-chemical.com China 44941 58
Shanghai Haohong Scientific Co., Ltd. 400-400-8210725
malulu@leyan.com China 39953 58

168960-18-7()キーワード:

(1R,4S)-N-BOC-1-アミノシクロペント-2-エン-4-カルボン酸 N-(tert-ブチルオキシカルボニル)-2-プロペン-1-アミン (1S,4R)-4-アミノ-2-シクロペンテン-1-メタノール
  • 168960-18-7
  • TERT-BUTYL CIS-[4(S)-(HYDROXYMETHYL)CYCLOPENT-2-EN-1(R)-YL]CARBAMATE
  • CARBAMIC ACID, [4(S)-(HYDROXYMETHYL)-2-CYCLOPENTEN-1-YL]-1,1-DIMETHYLETHYL ESTER, (1R-CIS)-
  • Carbamic acid, [(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1-
  • TERT-BUTYL (1R,4S)-4-(HYDROXYMETHYL)CYCLOPENT-2-ENYLCARBAMATE
  • tert-Butyl ((1R,4S)-4-(hydroxymethyl)cyclopent-2-en-1-yl)carbamate
  • (1R,4S)-N-(tert-Butyloxycarbonyl)-1-amino-4-(hydroxymethyl)-2-cyclopentene
  • 1-((1R,4S)-4-(Hydroxymethyl)cyclopent-2-en-1-yl)-2-methylpropan-2-yl carbamate
  • N-[(1R,4S)-4-(Hydroxymethyl)-2-cyclopenten-1-yl]-carbamic Acid 1,1-Dimethylethyl Ester
  • Carbamic acid, N-[(1R,4S)-4-(hydroxymethyl)-2-cyclopenten-1-yl]-, 1,1-dimethylethyl ester
Copyright 2017 © ChemicalBook. All rights reserved