Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) 物理性質
- 融点 :
- 123-125 °C
- 沸点 :
- 655.4±55.0 °C(Predicted)
- 比重(密度) :
- 1.38±0.1 g/cm3(Predicted)
- 酸解離定数(Pka):
- 9.19±0.10(Predicted)
安全性情報
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) 価格
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Bosutinib Impurity 2 (N-Desmethyl Bosutinib) 化学特性,用途語,生産方法
使用
Proteolysis Targeting Chimera (PROTAC) is a novel approach to modern drug development programs that utilizes small compounds to target proteins for ubiquitination and degradation by proteasome. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile is a PROTAC compound, which has the potential to target oncogenic BCR-ABL for degradation. 4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-3-quinolinecarbonitrile has also been employed in ligand-based pharmacophore modelling to identify c-Src inhibitors.
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) 上流と下流の製品情報
原材料
準備製品
Bosutinib Impurity 2 (N-Desmethyl Bosutinib) 生産企業
Global( 19)Suppliers
- 380843-81-2
- Bosutinib Impurity 2 (N-Desmethyl Bosutinib)
- Desmethyl Bosutinib
- 3-Quinolinecarbonitrile, 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(1-piperazinyl)propoxy]-