Crisaborole intermediate
Crisaborole intermediate 物理性質
- 沸点 :
- 432.1±55.0 °C(Predicted)
- 比重(密度) :
- 1.33±0.1 g/cm3(Predicted)
- 酸解離定数(Pka):
- 7.05±0.20(Predicted)
安全性情報
Crisaborole intermediate 価格
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Crisaborole intermediate 化学特性,用途語,生産方法
使用
5-(4-(Hydroxyl Methyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol is an impurity for Crisaborole(H947928). Crisaborole is a series of phenoxy benzoxaboroles were synthesized and screened for their inhibitory activity against PDE4 and cytokine release. 5-?(4-?Cyanophenoxy)?-?2,?3-?dihydro-?1-?hydroxy-?2,?1-?benzoxaborole (AN2728) showed potent activity both in vitro and in vivo. AN2728 is being studied as an anti-inflammatory agent.
Crisaborole intermediate 上流と下流の製品情報
原材料
準備製品
Crisaborole intermediate 生産企業
Global( 25)Suppliers
- 1187188-60-8
- 5-(4-(hydroxymethyl)phenoxy)benzo[c][1,2]oxaborol-1(3H)-ol
- 5-(4-(Hydroxylmethyl)phenoxy)benzo[c][1,2]oxaborol-1-(3H)-ol
- Crisaborole Impurity 59
- Crisaborole Impurity 37
- Crisaborole Impurity 28
- Benzenemethanol, 4-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-
- Creborol Impurity 28