Benzoic acid, (2Z)-2-(1,2-dihydro-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide
Benzoic acid, (2Z)-2-(1,2-dihydro-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide 物理性質
- 融点 :
- 134-135 °C
- 比重(密度) :
- 1.18±0.1 g/cm3(Predicted)
- 溶解性:
- DMF: 10 mg/ml; DMSO: 1 mg/ml; Ethanol: 1 mg/ml
- 外見 :
- A crystalline solid
- 酸解離定数(Pka):
- 10.45±0.20(Predicted)
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
Benzoic acid, (2Z)-2-(1,2-dihydro-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide 価格
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Benzoic acid, (2Z)-2-(1,2-dihydro-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide 化学特性,用途語,生産方法
使用
MDA-19 Pentyl Analogue is an impurity of MDA-19 (H295720), which is a selective agonist of the human peripheral cannabinoid (CB2) receptor. A cell-based functional assay showed MDA is an inverse agonist of the CB2 receptor in rat. Acts as an inverse agonist at the rat CB2 receptor. Reported Ki values are 16.3 and 1130 nM for human CB2 and CB1 receptor respectively. MDA19 was effective in attenuating tactile allodynia in neuropathic rats. MDA19 thus has potential for alleviating neuropathic pain without producing adverse effects in the central nervous system. Synthetic Cannabinoids. MDA-19 Pentyl Analogue can modulate cannabinoid receptors.
Benzoic acid, (2Z)-2-(1,2-dihydro-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide 上流と下流の製品情報
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Benzoic acid, (2Z)-2-(1,2-dihydro-2-oxo-1-pentyl-3H-indol-3-ylidene)hydrazide 生産企業
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