tubifoline 化学特性,用途語,生産方法
説明
This alkaloid from the leaf extract of Pleiocarpa pycnantha (K. Schum) Stapf.
var. tubicina (Stapf.) Pichon is the dehydro derivative of the preceding base. It
yields colourless crystals from pantane which may be further purified by sublima_x0002_tion. It is strongly laevorotatory with [α]
23D - 342° (c0.549, CHCI3). The
methiodide forms colourless crystals from Et20-Me2CO, m.p. 25l-3°C (dec.).
As before, the structure has been confirmed by synthesis of the optically active
form.
参考文献
Weissmann, Schmid, Karrer., Helv. Chim. Acta, 44, 1877 (1961)
Kump et al., ibid, 47, 1497 (1964)
Synthesis:
Dadson, Harley-Mason, Foster., Chem. Commun., 1233 (1968)
tubifoline 上流と下流の製品情報
原材料
準備製品