1-(2,3,4-TRIHYDROXYPHENYL)PROPAN-1-ONE 化学特性,用途語,生産方法
製造方法
Preparation by acylation of pyrogallol with propionic acid
in the presence of boron trifluoride in ethyl ether for 1 h at 0° (80%)
in the presence of Amberlite IR-120 (cation exchange resin sulfonic acid ? type) at 160° for 2–3 h (78%)
Zeokarb 225 was found to be as effective
in the presence of zinc chloride, at 130–140° for 90 min (Nencki ? reaction) (35%)
in the presence of 70% perchloric acid at reflux for 1 h (33%)
Preparation by reaction of propionyl chloride with pyrogallol and heating 4 h on a water bath (75%)
Preparation by acylation of pyrogallol with propionic anhydride
in the presence of Amberlite IR-120 (cation exchange resin sulfonic acid type) ? at 160° for 2–3 h (79%)
Zeokarb 225 was found to be as effective
in the presence of concentrated sulfuric acid (small drops) at 130° for some ? min (65%)
in the presence of zinc chloride, but using a mixture of propionic acid/propionic ? anhydride (85/100) at 135–140° for 40 min, then at r.t. overnight (59%).
1-(2,3,4-TRIHYDROXYPHENYL)PROPAN-1-ONE 上流と下流の製品情報
原材料
準備製品