MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体
MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体 物理性質
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H317 |
アレルギー性皮膚反応を起こすおそれ |
感作性、皮膚 |
1 |
警告 |
 |
P261, P272, P280, P302+P352,P333+P313, P321, P363, P501 |
| H334 |
吸入するとアレルギー、喘息または、呼吸困難 を起こすおそれ |
感作性、呼吸器 |
1 |
危険 |
|
P261, P285, P304+P341, P342+P311,P501 |
|
| 注意書き |
| P261 |
粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。 |
| P272 |
汚染された作業衣は作業場から出さないこと。 |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
| P284 |
呼吸用保護具を着用すること。 |
| P302+P352 |
皮膚に付着した場合：多量の水と石鹸で洗うこと。 |
| P333+P313 |
皮膚刺激または発疹が生じた場合：医師の診断/手当てを 受けること。 |
|
MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体 価格
もっと(1)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
G9295 |
モノクロナール抗GAPDH−ペルオキシダーゼ マウス宿主抗体 clone GAPDH-71.1, purified immunoglobulin, buffered aqueous solution
Monoclonal Anti-GAPDH−Peroxidase antibody produced in mouse clone GAPDH-71.1, purified immunoglobulin, buffered aqueous solution |
|
200μL |
￥134000 |
2024-03-01 |
購入 |
MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体 化学特性,用途語,生産方法
使用
Monoclonal Anti-GAPDH-Peroxidase antibody produced in mouse has been used in
- immunoblotting
- enzyme linked immunosorbent assay (ELISA)
- immunocytochemistry
一般的な説明
Monoclonal Anti-GAPDH (mouse IgM isotype) is derived from the hybridoma GAPDH-71.1 produced by the fusion of mouse myeloma cells (NS1 cells) and splenocytes from BALB/c mice immunized with rabbit GAPDH.
Biochem/physiol Actions
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a tetramer containing identical chains. It catalyzes the reversible oxidative phosphorylation of glyceraldehyde-phosphate, which is a critical energy-yielding step in carbohydrate metabolism. It binds to several proteins including actin, tubulin, amyloid precursor, polyglutamine peptides, DRPLA (dentatorubral-pallidoluysian atrophy), and huntingtin. Protein kinase Cι/λbinds and phosphorylates GAPDH. Phosphorylated GAPDH associates with cytoskeletal elements and controls microtubule dynamics in the early secretory pathway. Poly(ADP-ribose) polymerase-1 (PARP1) interacts with GAPDH and thereby mediates brain damage in the presence of oxidative/nitrosative stress. GAPDH forms a part of OCA-S, the multicomponent OCT1 (octamer-motif-binding factor) coactivator complex, which is involved in the S phase-dependent histone H2B transcription. This association is responsible for linking H2B transcriptional machinery to cell cycle regulation and to the cellular metabolic state. GAPDH is also a component of the functional GAIT (interferon-γ-activated inhibitor of translation) mRNP (messenger ribonucleoprotein). GAPDH expression is dysregulated during melanoma progression.
MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体 上流と下流の製品情報
原材料
準備製品
MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体 生産企業
Global( 1)Suppliers
(MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体)キーワード:
- Anti-G3PD, Anti-G3PDH, Anti-Glyceraldehyde-3-phosphate Dehydrogenase
- Monoclonal Anti-GAPDH-Peroxidase antibody produced in mouse
- Monoclonal Anti-GAPDH antibody produced in mouse
- MONOCLONAL ANTI-GAPDH−PEROXIDASE マウス宿主抗体