(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート 物理性質
- 融点 :
- ca 160℃
- 貯蔵温度 :
- Store at -15°C to -25°C.
- 溶解性:
- 2mL中1mmolのDMFに可溶。
- 外見 :
- 粉末または固体
- 色:
- 白色～淡黄色
- Sensitive :
- Air & Moisture Sensitive
- InChI:
- InChI=1S/C12H19N4O4.F6P/c1-4-19-11(17)10(9-13)14-20-12(15(2)3)16-5-7-18-8-6-16;1-7(2,3,4,5)6/h4-8H2,1-3H3;/q+1;-1/b14-10-;
- InChIKey:
- GPDHNZNLPKYHCN-DZOOLQPHSA-N
- SMILES:
- C1N(/C(/O/N=C(\C(OCC)=O)/C#N)=[N+](\C)/C)CCOC1.[P-](F)(F)(F)(F)(F)F
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート 価格
もっと(10)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01BCS4062545 |
COMU |
1075198-30-9 |
5g |
￥22000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01BCS4062545 |
COMU |
1075198-30-9 |
25g |
￥89000 |
2024-03-01 |
購入 |
|
東京化成工業
|
C2733 |
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート >98.0%(N)
(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.)
>98.0%(N) |
1075198-30-9 |
5g |
￥5900 |
2024-03-01 |
購入 |
|
東京化成工業
|
C2733 |
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート >98.0%(N)
(1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.)
>98.0%(N) |
1075198-30-9 |
25g |
￥20500 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
712191 |
97%
COMU? 97% |
1075198-30-9 |
5g |
￥5870 |
2024-03-01 |
購入 |
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート 化学特性,用途語,生産方法
外観
白色, 結晶～粉末
溶解性
エタノールにほとんど溶けず、水に溶けない。
使用上の注意
アルゴン封入
説明
COMU is a third-generation uronium-type coupling reagent based on ethyl 2-cyano-2-(hydroxylamine)acetate (Oxyma) and a morpholino carbon skeleton. The presence of the morpholino group has a marked influence on the reagent's solubility, stability, and reactivity. COMU performed exceptionally well in the presence of only 1 equiv of base, confirming the effect of the hydrogen bond acceptor in the reaction. The by-products of COMU are water soluble and easily removed, making it an excellent choice of coupling reagent for solution-phase peptide synthesis[1].
使用
COMU – Safer and More Efficient Peptide Coupling ReagentAdvantages
- Equal or even superior performance to HATU
- Non-explosive (does not contain benzotriazole moiety)
- Suitable for solution phase & solid phase peptide synthesis
- Utmost retention of configuration – low to non-existent racemization
- High solubility and stability in typical solvents
- Visual or colorimetric reaction monitoring possible
- Easy removal of water-soluble by-products
一般的な説明
This product is a Safer, non-explosive and more effective replacement for Benzotriazole-Based peptide coupling reagents and thus aligns with "Less Hazardous Chemical Synthesis" and "Inherently Safer Chemistry for Accident Prevention".
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート 上流と下流の製品情報
原材料
準備製品
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート 生産企業
Global( 152)Suppliers
(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート スペクトルデータ(FT-IR)
- 1075198-30-9
- (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylamino-morpholino-carbenium hexafluorophosphate
- 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxayl] (dimethylamino)methylene]-hexafluorophosphate
- 1-[1-(Cyano-2-ethoxy-2-oxoethylideneaMinooxy)-diMethylaMino-Morpholino]-uroniuM hexafluorophosphate
- (1-Cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium Hexafluorophosphate (This product is only available in Japan.)
- COMU(R) 97%
- elagolix intermediate 13
- COMU
4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium
- [[(Z)-(1-Cyano-2-ethoxy-2-oxo-ethylidene)amino]oxy-morpholino-methylene]-dimethyl-ammonium hexafluorophosphate
- [[(Z)-(1-cyano-2-ethoxy-2-oxoethylidene)amino]oxy-morpholin-4-ylmethylidene]-dimethylazanium
- 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium
- COMU ISO 9001：2015 REACH
- COMU NOVABIOCHEM(R) 25 G
- COMU
4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium,98%
- 4-(6-Cyano-2-methyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-ylidene)morpholin-4-ium hexafluorophosphate
- {[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxy}dimethylamino(morpholin-4-yl)carbenium hexafluorophosp
- 4-{{[(1-Cyano-2-ethoxy-2-oxoethylidene)-amino]-oxayl}-(dimethylamino)-methylene}-hexafluorophosphate morpholinium(COMU?)
- {{[(1-Cyano-2-ethoxy-2-oxoethylidene)amino]oxy}-4-morpholinomethylene}dimethylammonium
- [[(Z)-(1-cyano-2-ethoxy-2-oxoethylidene)amino]oxy-morpholin-4-ylmethylidene]-dimethylazanium,hexafluorophosphate
- 4-(6-Cyano-2-methyl-7-oxo-4,8-dioxa-2,5-diazadec-5-en-3-ylidene)morpholin-4-ium hexafluorophosphate(V)
- N-1-(Cyano-2-ethoxy-2-oxoethylideneaminooxy)dimethylamino(morpholin-4-yl)uronium hexafluorophosphate
- (2-oxime cyanoacetate ethyl ester) - N, N-dimethylmorpholineurea hexafluorophosphate
- (1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)ジメチルアミノモルホリノカルベニウムヘキサフルオロホスファート
- {{[(1-シアノ-2-エトキシ-2-オキソエチリデン)アミノ]オキシ}-4-モルホリノメチレン}ジメチルアンモニウムヘキサフルオロりん酸塩
- 1-[(1-(シアン-2-エトキシ-2-オクソエチリデンアミノオキシ)ジメチルアミノモルホリノ)]ウロニウムヘキサフルオロホスファート
- ジメチルアミノ(1-シアノ-2-エトキシ-2-オキソエチリデンアミノオキシ)モルホリノメチリウム・ヘキサフルオロホスファート
- (ジメチルアミノ)モルホリノ[[(1-シアノ-2-オキソ-2-エトキシエチリデン)アミノ]オキシ]メチルカチオン・ヘキサフルオロホスファート