7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride

7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride 価格 もっと(4)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	SML0571	≥98% (HPLC) SB-612111 hydrochloride ≥98% (HPLC)	371980-98-2	5mg	￥33900	2024-03-01	購入
Sigma-Aldrich Japan	SML0571	≥98% (HPLC) SB-612111 hydrochloride ≥98% (HPLC)	371980-98-2	25mg	￥88600	2024-03-01	購入
富士フイルム和光純薬株式会社(wako)	W01TOC3573	SB 612111 hydrochloride	371980-98-2	10mg	￥66000	2021-03-23	購入
富士フイルム和光純薬株式会社(wako)	W01TOC3573	SB 612111 hydrochloride	371980-98-2	50mg	￥281000	2021-03-23	購入

7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride 化学特性,用途語,生産方法

使用

A selective nociceptin/orphanin FQ receptor antagonist, 7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride can act as a potentially useful adjunct to chronic pain therapy with opioids and can be used to treat conditions in which thermal hyperalgesia is a significant component of the pain response.

Biochem/physiol Actions

SB-612111 is a potent antagonist of the nociceptin receptor ORL-1. SB-612111 binds to ORL-1 with high affinity (Ki = 0.33 nM) but has very low affinity for classic opioid receptors. The compound SB-612111 antagonizes the anti-morphine effects of nociceptin and blocks nociceptin-induced thermal hyperalgesia.

7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride 上流と下流の製品情報

原材料

準備製品

7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9900	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9708	58
Amatek Scientific Co. Ltd.	0512-56316828	info@amateksci.com	China	28819	58
Aishilun biotechnology (Shanghai) co., LTD	021-50676523 18019098996	info@acelybio.com	China	3967	58
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
Wuhan Topule	+86-02787215551 +86-19945035818	2936752263@qq.com	China	8234	58

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• 371980-98-2
• 7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-olhydrochloride
• SB 612111 hydrochloride
• SB 612111
• (-)-cis-1-Methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]Methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol Hydrochloride
• (5S,7S)-7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]Methyl]-6,7,8,9-tetrahydro-1-Methyl-5H-benzocyclohepten-5-ol Hydrochloride
• (5S,7S)-7-[[4-(2,6-Dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-5H-benzocyclohepten-5-ol
• (5S,7S)-7-((4-(2,6-DICHLOROPHENYL)PIPERIDIN-1-YL)METHYL)-1-METHYL-6,7,8,9-TETRAHYDRO-5H-BENZO[7]ANNULEN-5-OL HCL
• 5H-Benzocyclohepten-5-ol, 7-[[4-(2,6-dichlorophenyl)-1-piperidinyl]methyl]-6,7,8,9-tetrahydro-1-methyl-, (5S,7S)-
• SB612111,SB 612111