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GW610

GW610 化学構造式
872726-44-8
CAS番号.
872726-44-8
化学名:
GW610
别名:
GW610;5-フルオロ-2-(3,4-ジメトキシフェニル)ベンゾチアゾール;2-(3,4-ジメトキシフェニル)-5-フルオロ-1,3-ベンゾチアゾール;2-(3,4-ジメトキシフェニル)-5-フルオロベンゾチアゾール
英語名:
GW 610
英語别名:
GW 610;NSC 721648;NSC 721648 PMX 610;NSC 721648 - CAS 872726-44-8 - Calbiochem;2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole;Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro-;GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648
CBNumber:
CB72591189
化学式:
C15H12FNO2S
分子量:
289.3246832
MOL File:
872726-44-8.mol

GW610 物理性質

融点 :
110 °C
沸点 :
422.8±55.0 °C(Predicted)
比重(密度) :
1.293±0.06 g/cm3(Predicted)
貯蔵温度 :
+2C to +8C
溶解性:
DMF:10.0(Max Conc. mg/mL);34.56(Max Conc. mM)
DMF:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.86(Max Conc. mM)
DMSO:9.5(Max Conc. mg/mL);32.84(Max Conc. mM)
外見 :
白色結晶性固体
酸解離定数(Pka):
0.73±0.10(Predicted)
色:
Light yellow to brown

安全性情報

GW610 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TRCG929500 GW610
GW 610 		872726-44-8 10mg ￥41300 2023-06-01 購入
富士フイルム和光純薬株式会社(wako) W01TRCG929500 GW610
GW 610 		872726-44-8 100mg ￥317400 2023-06-01 購入

GW610 化学特性,用途語,生産方法

説明

GW 610 is an antitumor benzothiazole that shows growth-inhibitory activity against several cancer cell lines. In MCF-7 and MDA 468 human cancer cell lines, potent antiproliferative activity (growth inhibition (GI50) < 0.1 nM) was observed. Potent and selective activity was also observed in the NCI 60 human cancer cell line panel. In contrast with previously reported 2-(4-aminophenyl)benzothiazoles, GW 610 is not reliant on induction of cytochrome P 1A1 (CYP1A1) expression for antitumor activity.

使用

GW 610 is a fluorinated 2-arylbenzothiazole and potential antitumor drug, which shows potent and selective inhibitory activity against breast, lung, and colon cancer cell lines. Studies suggest that the species-specific partial agonism of the aryl hydrocarbon receptor shown by GW 610 plays an important role in its anti-proliferative activity.

GW610 上流と下流の製品情報

原材料

準備製品

GW610 生産企業

Global( 47)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
Dongying Sifang Litong New Material Co. LTD 13589435123 17861826421
 dysflt@126.com China 287 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
 jkinfo@jkchemical.com China 96815 76
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979
info@tsbiochem.com China 8073 58
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720
 klq@cw-bio.com China 3717 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
 sales@rrkchem.com China 56057 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
 order@med-bio.cn China 8141 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233
 3362556465@qq.com China 8000 58
Bide Pharmatech Ltd. 400-1647117 15221909166
 product02@bidepharm.com China 63720 58

GW610  スペクトルデータ(1HNMR)

GW 610(872726-44-8)1HNMR
  • 872726-44-8
  • GW 610
  • NSC 721648
  • NSC 721648 - CAS 872726-44-8 - Calbiochem
  • NSC 721648 PMX 610
  • GW 610,colon,Inhibitor,GW610,NSC721648,inhibit,breast,antitumor,NSC 721648,lung,GW-610,NSC-721648
  • Benzothiazole, 2-(3,4-dimethoxyphenyl)-5-fluoro-
  • 2-(3,4-Dimethoxyphenyl)-5-fluorobenzo[d]thiazole
  • GW610
  • 5-フルオロ-2-(3,4-ジメトキシフェニル)ベンゾチアゾール
  • 2-(3,4-ジメトキシフェニル)-5-フルオロ-1,3-ベンゾチアゾール
  • 2-(3,4-ジメトキシフェニル)-5-フルオロベンゾチアゾール
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