(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
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- CAS番号.
- 874638-94-5
- 化学名:
- 别名:
- 英語名:
- (2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
- 英語别名:
- Sofosbuvir imp-6;Sofosbuvir Impurity X;2'-epi-Sofosbuvir Desphosphate;Sofosbuvir Dibenzoyl Amino Impurity;(2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((be...;(2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate;Benzamide, N-[1-[(2R)-3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-;N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-alpha-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide;Sofosbuvir impurity 21/(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
- CBNumber:
- CB72705027
- 化学式:
- C31H26FN3O7
- 分子量:
- 571.56
- MOL File:
- 874638-94-5.mol
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(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate 物理性質
- 融点 :
- 174-175 °C(Solv: dichloromethane (75-09-2); hexane (110-54-3))
- 比重(密度) :
- 1.34±0.1 g/cm3(Predicted)
- 酸解離定数(Pka):
- 8.51±0.20(Predicted)
安全性情報
(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate 価格
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(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate 化学特性,用途語,生産方法
使用
2’-epi-Sofosbuvir Desphosphate is possible metabolite of Sofosbuvir (P839640) which is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C.
(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate 上流と下流の製品情報
原材料
準備製品
(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate 生産企業
Global( 59)Suppliers
874638-94-5()キーワード:
ソホスブビル
イソプロピル＝Ｎ－［（ペンタフルオロフェノキシ）（フェノキシ）ホスホリ ル］－Ｌ－アラニナート
2,3,5-トリ-O-ベンゾイル-2-C-メチル-D-リボン酸-1,4-ラクトン
4-クロロ安息香酸((2R,3R,4R)-3-((4-クロロベンゾイル)オキシ)-4-フルオロ-4-メチル-5-オキソテトラヒドロフラン-2-イル)メチル
2,3,4,5-テトラフルオロフェノール
りん酸ジメチル(フェニル)
1,3,5-トリ-O-ベンゾイル-α-D-リボフラノース
(2'R)-2'-デオキシ-2'-フルオロ-2'-メチルウリジン
(2'R)-N-ベンゾイル-2'-デオキシ-2'-フルオロ-2'-メチルシチジン3',5'-二安息香酸
安息香酸((2R,3R,4R)-3-(ベンゾイルオキシ)-4-フルオロ-4-メチル-5-オキソテトラヒドロフラン-2-イル)メチル
- 874638-94-5
- N-[1-[(2R)-3,5-Di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-alpha-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]benzamide
- 2'-epi-Sofosbuvir Desphosphate
- Sofosbuvir Impurity X
- Sofosbuvir impurity 21/(2R,3R,4R,5S)-5-(4-benzaMido-2-oxopyriMidin-1(2H)-yl)-2-((benzoyloxy)Methyl)-4-fluoro-4-Methyltetrahydrofuran-3-yl benzoate
- Sofosbuvir imp-6
- Benzamide, N-[1-[(2R)-3,5-di-O-benzoyl-2-deoxy-2-fluoro-2-methyl-α-D-erythro-pentofuranosyl]-1,2-dihydro-2-oxo-4-pyrimidinyl]-
- Sofosbuvir Dibenzoyl Amino Impurity
- (2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((be...
- (2R,3R,4R,5S)-5-(4-Benzamido-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4-fluoro-4-methyltetrahydrofuran-3-yl benzoate