Anti-POU domain, class 2, transcription factor 2

Anti-POU domain, class 2, transcription factor 2 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	WH0005452M1	clone 3E3-6F9, purified immunoglobulin, buffered aqueous solution Monoclonal Anti-POU2F2 antibody produced in mouse clone 3E3-6F9, purified immunoglobulin, buffered aqueous solution		100μG	￥78600	2024-03-01	購入

Anti-POU domain, class 2, transcription factor 2 化学特性,用途語,生産方法

使用

Monoclonal Anti-SLC22A2 antibody produced in mouse has been used in immunostaining.

一般的な説明

Solute carrier family 22 member 2 (SLC22A2) also known as organic cation transporter 2 (OCT2), is expressed prominently in the basolateral membrane of epithelial cells of kidney, especially in the proximal renal tubule. SLC22A2 possess 12 transmembrane domains and is the integral plasma membrane protein. In the human, SLC22A2 gene is mapped to chromosome 6q26.

Biochem/physiol Actions

Solute carrier family 22 member 2 (SLC22A2) is involved in the transport of cationic substances like drugs, toxins, waste metabolites like creatinine, neurotransmitters etc., from the kidney. Expression of SLC22A2 in kidney is regulated by methylation of the promoter region. The major substrate for SLC22A2 is metformin, an anti-diabetic agent. Lack of SLC22A2 leads possibly to drug toxicity as these substances are not eliminated from the body. Imipramine, clonidine, verapamil, quinidine, carvedilol, interact with SLC22A2 by hydrophobic interaction and leads to its inhibition.

Anti-POU domain, class 2, transcription factor 2 上流と下流の製品情報

原材料

準備製品

Anti-POU domain, class 2, transcription factor 2 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shanghai guandao biology engineering co., ltd	18818239863 18818239863	3171921642@qq.com	China	8889	58

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• Anti-2-Oct
• Anti-39723
• Anti-OTF2
• Anti-POU domain, class 2, transcription factor 2
• Monoclonal Anti-POU2F2 antibody produced in mouse
• Anti-MGC32628
• Anti-solute carrier family 22 (organic cation transporter), member 2
• Monoclonal Anti-SLC22A2 antibody produced in mouse