AZ9482 化学特性,用途語,生産方法
説明
AZ9482 is a poly(ADP-ribose) polymerase (PARP) inhibitor (IC
50s = 1, 1, 46, 640, 9, and 160 nM for PARP1, -2, -3, -6, TNKS1/PARP5a, and TNKS2, respectively). It induces centrosome declustering (EC
50 = <18 nM) and a multipolar spindle phenotype in HeLa cells. AZ9482 inhibits the growth of OCI-LY19 diffuse large B cell lymphoma (DLBCL) cells (GI
50 = 3 nM).
AZ9482 上流と下流の製品情報
原材料
準備製品