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ロチラナー

ロチラナー 化学構造式
1369852-71-0
CAS番号.
1369852-71-0
化学名:
ロチラナー
别名:
ロチラナー
英語名:
Lotilaner
英語别名:
Lotilaner;Lotilaner (TP-05);Parasite,Inhibitor,γ-Aminobutyric acid Receptor,Lotilaner,inhibit,Gamma-aminobutyric acid Receptor,GABA Receptor;(S)-3-Methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)a mino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluo romethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2- carboxamide;2-Thiophenecarboxamide, 5-[(5S)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-;(S)-5-[5-(3,4,5-trichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-3-methyl-thiophene-2-carboxylic acid [(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-amide
CBNumber:
CB73344768
化学式:
C20H14Cl3F6N3O3S
分子量:
596.76
MOL File:
1369852-71-0.mol

ロチラナー 物理性質

比重(密度) :
1.66±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMSO : ≥ 100 mg/mL (167.57 mM)
外見 :
Solid
酸解離定数(Pka):
12.52±0.46(Predicted)
色:
White to off-white

安全性情報

ロチラナー 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

ロチラナー 化学特性,用途語,生産方法

効能

抗寄生虫薬

説明

Lotilaner is a representative of the isoxazolines, a new class of insecticides discovered in the 2000s.
Isoxazolines (Afoxolaner, Fluralaner, Lotilaner, and Sarolaner) Isoxazolines are insecticidal and arachnicidal substances that can be given orally, or topically as spot-ons, and act systemically in the blood circulation.
lotilaner (Credeliot), a novel oral isoxazoline against naturally occurring mange mite infestations in dogs caused by Demodex spp.
Lotilaner, like the other isooxazolines is active against fleas, mites, and ticks. After oral administration or topical application, it can kill fleas rapidly.

使用

Lotilaner is a new member of the isoxazoline class for the treatment of flea and tick infestations in cats.

適応症

Lotilaner is a monthly chewable tablet for the treatment and prevention of fleas and ticks. It is used in dogs and puppies 8 weeks of age or older weighing 4.4 pounds or greater (Elanco, 2019).

副作用

These include weight loss, elevated blood urea nitrogen, increased urination, and diarrhea (Elanco, 2019).

ロチラナー 上流と下流の製品情報

原材料

2-Thiophenecarboxylic acid, 5-[4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl- Isoxazole, 3-(5-bromo-4-methyl-2-thienyl)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)- 5-ブロモ-3-メチルチオフェン-2-カルボン酸 2-アミノ-N-(2,2,2-トリフルオロエチル)アセトアミド塩酸塩

準備製品

ロチラナー 生産企業

Global( 77)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
Shaanxi Dideu Medichem Co. Ltd 		+86-29-81148696 +86-15536356810
 1022@dideu.com China 3882 58
Jinan Million Pharmaceutical Co., Ltd 		0531-68659554 +8613031714605
 info@millionpharm.com China 254 58
BOC Sciences 		+1-631-485-4226
inquiry@bocsci.com United States 19553 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196
 sale04@alfachem.cn China 11885 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695
 laboratory@coreychem.com China 30238 58
Shanghai UCHEM Inc. 		+862156762820 +86-13564624040
 sales@myuchem.com China 7688 58
Xi'an MC Biotech, Co., Ltd. 		029-89275612 +8618991951683
 mcbio_sales@163.com China 2251 58
Hebei Lingding Biotechnology Co., Ltd. 		+86-18031140164 +86-19933155420
 erin@hbldbiotech.com China 66 58
Hainan Mike Biomedical Technology Co., Ltd 		+86-15120707353 +86-18876637353
 tunanmedicine@hotemail.com China 43 58

ロチラナー  スペクトルデータ(1HNMR)

Lotilaner(1369852-71-0)1HNMR
  • 1369852-71-0
  • Lotilaner
  • (S)-5-[5-(3,4,5-trichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-3-methyl-thiophene-2-carboxylic acid [(2,2,2-trifluoro-ethylcarbamoyl)-methyl]-amide
  • 2-Thiophenecarboxamide, 5-[(5S)-4,5-dihydro-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-3-isoxazolyl]-3-methyl-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-
  • Parasite,Inhibitor,γ-Aminobutyric acid Receptor,Lotilaner,inhibit,Gamma-aminobutyric acid Receptor,GABA Receptor
  • (S)-3-Methyl-N-(2-oxo-2-((2,2,2-trifluoroethyl)a mino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluo romethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2- carboxamide
  • Lotilaner (TP-05)
  • ロチラナー
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