DNAジャイレース 化学特性,用途語,生産方法
性質
A2B2 構造．ATP依存で環状DNAに負のスーパーコイルを導入．活性基はA-Tyr122
天然物の起源
E. coli, A鎖：1～875, B鎖：1～804
使用
DNA gyrase from
Escherichia coli has been used in a study to investigate a comparative proteomic approach to better define Deinococcus nucleoid specificities. DNA gyrase from
Escherichia coli has also been used in a study to investigate the role of the DnaK-ClpB bichaperone system in DNA gyrase reactivation.
Biochem/physiol Actions
DNA gyrase is supplied as an A2B2 holoenzyme. The molecular mass of subunit A is 97 kDa and that of subunit B is 90 kDa. It catalyzes the ATP-dependent introduction of negative supercoils into relaxed DNA. DNA gyrase has been successfully converted into a type II topoisomerase by mutagenesis experiments.
DNAジャイレース 上流と下流の製品情報
原材料
準備製品