4-ヒドロキシブタン酸ナトリウム
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- CAS番号.
- 502-85-2
- 化学名:
- 4-ヒドロキシブタン酸ナトリウム
- 别名:
- γ-ヒドロキシ酪酸ナトリウム;4-ヒドロキシブタン酸ナトリウム;ナトリウム4-ヒドロキシブチラート;オキシバートナトリウム;ソムサムニット;ガンマ-OH;γ-ヒドロキシブタン酸ナトリウム;4-ヒドロキシ酪酸ナトリウム;4-ヒドロキシ酪酸, ナトリウム塩;ガンマヒドロキシ酪酸ナトリウム
- 英語名:
- SODIUM 4-HYDROXYBUTYRATE
- 英語别名:
- GHB;SODIUM OXYBATE;SODIUM 4-HYDROXYBUTANOATE;gammaoh;wy-3478;somsanit;NSC-84223;GHB SODIUM SALT;Oxybate (sodium);Levetiracetam-15
- CBNumber:
- CB7491645
- 化学式:
- C4H9NaO3
- 分子量:
- 128.1
- MOL File:
- 502-85-2.mol
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安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
主な危険性 |
F,T |
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Rフレーズ |
11-23/24/25-39/23/24/25 |
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Sフレーズ |
22-24/25-45-36/37-16-7 |
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RIDADR |
UN1230 - class 3 - PG 2 - Methanol, solution |
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WGK Germany |
2 |
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RTECS 番号 |
ET4750000 |
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F |
3 |
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国連危険物分類 |
IRRITANT |
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毒性 |
Highly sol in aq solns. LD50 in male, female rats (mg/kg): 2,000, 1,650 i.p. (Bruguerolle) |
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絵表示(GHS) |
![GHS hazard pictograms](/GHS02.jpg) ![GHS hazard pictograms](/GHS06.jpg)
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注意喚起語 |
危険 |
危険有害性情報 |
コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
H225 |
引火性の高い液体および蒸気 |
引火性液体 |
2 |
危険 |
![](/GHS02.jpg) |
P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
H370 |
臓器の障害 |
特定標的臓器有害性、単回暴露 |
1 |
危険 |
![](/GHS08.jpg) |
P260, P264, P270, P307+P311, P321,P405, P501 |
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注意書き |
P210 |
熱/火花/裸火/高温のもののような着火源から遠ざ けること。-禁煙。 |
P260 |
粉じん/煙/ガス/ミスト/蒸気/スプレーを吸入しないこ と。 |
P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
P301+P310 |
飲み込んだ場合:直ちに医師に連絡すること。 |
P311 |
医師に連絡すること。 |
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4-ヒドロキシブタン酸ナトリウム 化学特性,用途語,生産方法
効能
補助麻酔薬
説明
Xyrem is distributed by Jazz Pharmaceuticals, Inc. (Palo Alto,
CA). It is an oral solution of sodium oxybate prescribed for
narcoleptic patients to treat extreme daytime sleepiness and
cataplexy. Xyrem is also known as sodium oxybate which is the
same as gamma hydroxybutyric acid (GHB), a drug of abuse.
GHB is endogenously produced and present in the central
nervous system (CNS) in small concentrations. Accidental
overdosing has led to many hospitalizations and deaths.
Because of the tendency to abuse GHB, it was classified as
a schedule I controlled substance. This meant that GHB had
a high potential for abuse and no medical purpose. However,
in 2002, because of a series of clinical trials that demonstrated
that the compound reduces cataplexy attacks, it was approved
for use under the trademark Xyrem. Since GHB had previously
been used as a ‘date-rape’ drug, Xyrem is considered a schedule
III controlled substance and is distributed in accordance with
strict FDA regulations. Xyrem may only be ordered through the
‘Xyrem Success Program.’ Illegal use is punishable under
federal and state laws.
化学的特性
white crystalline powder
使用
4-Hydroxybutyric acid sodium salt is an agonist to both GHB and GABAB neural receptors, exhibiting neurotransmitter-like effects. It has been used as a general anesthetic in treatment for sleep disorders and clinical depression, but also has been identified as a “date rape drug”.
環境運命予測
Xyrem is a water-soluble white to off-white powder, which can
be disposed by dumping the oral solution down the sanitary
sewer system. This is the preferred method of disposal for drugs
which have a high potential for abuse and/or accidental
overdose.
4-ヒドロキシブタン酸ナトリウム 上流と下流の製品情報
原材料
準備製品
4-ヒドロキシブタン酸ナトリウム スペクトルデータ(1HNMR、13CNMR、IR1、IR2、IR3)
502-85-2(4-ヒドロキシブタン酸ナトリウム)キーワード:
- 502-85-2
- 4-hydroxy-butanoicacimonosodiumsalt
- 4-hydroxy-butyricacisodiumsalt
- γ-Hydroxybutyric acid sodium salt
- GAMMA-HYDROXYBUTYRIC ACID SODIUM
- Sodium4-hydroxybutyrate,98%
- Butanoic acid, 4-hydroxy-, monosodium salt
- GHB,1.0MG/MLINMETHANOL
- Sodium oxybutryrate (gamma)
- γ-Hydroxybutyric acid sodium salt, 4-Hydroxybutyric acid sodium salt, GHB, Sodium 4-hydroxybutyrate
- 4-Hydroxybutanoic acid sodium
- NSC-84223
- 4-Hydroxybutyric acid, sodium salt,99%
- Methanol (test GHB Sodium Salt, 1.0 mg/mL)
- Sodium g-hydroxybutyrate (GHB)
- 4-Hydroxybutyrate sodium
- 4-Hydroxybutyric acid monosodium salt
- Butanoic acid,4-hydroxy-, sodiuM salt (1:1)
- GHB SODIUM SALT
- GAMMA-HYDROXYBUTYRIC ACID SODIUM SALT
- 4-Hydroxybutyric acid sodium salt solution
- GHB sodium salt solution
- Oxybate (sodium)
- gamma-hydroxybutyratesodiumsalt
- gammaoh
- sodiumgamma-hydroxybutyrate
- somsanit
- wy-3478
- 4-HYDROXYBUTANOIC ACID SODIUM SALT
- 4-HYDROXYBUTYRIC ACID SODIUM SALT
- SODIUM 4-HYDROXYBUTYRATE
- γ-ヒドロキシ酪酸ナトリウム
- 4-ヒドロキシブタン酸ナトリウム
- ナトリウム4-ヒドロキシブチラート
- オキシバートナトリウム
- ソムサムニット
- ガンマ-OH
- γ-ヒドロキシブタン酸ナトリウム
- 4-ヒドロキシ酪酸ナトリウム
- 4-ヒドロキシ酪酸, ナトリウム塩
- ガンマヒドロキシ酪酸ナトリウム
- 麻酔薬