ザラゴジン酸A 三ナトリウム塩 化学特性,用途語,生産方法
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Zaragozic acid A trisodium salt is a potent inhibitor of squalene synthase.
Biochem/physiol Actions
Potent inhibitor, in vivo and in vitro, of mammalian, fungal and Saccharomyces cervisiae squalene synthase. Squalene synthase is the first committed enzyme in sterol synthesis, catalyzing the reductive condensation of farnesyl pyrophosphate to form squalene. As a squalene synthase inhibitor, zaragozic acid produces lower plasma cholesterol levels in primates. Treatment of rats with zaragozic acid A caused an increase in hepatic low density lipoprotein (LDL) receptor mRNA levels.
ザラゴジン酸A 三ナトリウム塩 上流と下流の製品情報
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