リンコシン塩酸塩
リンコシン塩酸塩 物理性質
- 融点 :
- 156-158C
- 貯蔵温度 :
- 2-8°C
- 溶解性:
- H2O: 50 mg/mL 無色透明
- 外見 :
- 個体
- 色:
- 黄色かぶりのある白から白
- 水溶解度 :
- 水に溶ける。
- BRN :
- 4171650
- 安定性：:
- 吸湿性
- InChIKey:
- POUMFISTNHIPTI-BOMBIWCESA-N
- SMILES:
- [C@]([H])([C@]1([H])[C@@H]([C@H](O)[C@@H](O)[C@@H](SC)O1)O)([C@H](O)C)NC([C@H]1N(C[C@H](CCC)C1)C)=O.Cl |&1:0,2,4,5,7,9,14,19,22,r|
- EPAの化学物質情報:
- D-erythro-.alpha.-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, hydrochloride (1:1) (859-18-7)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCL466200 |
リンコマイシン塩酸塩
Lincomycin Hydrochloride |
859-18-7 |
50mg |
￥21900 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCL466200 |
リンコマイシン塩酸塩
Lincomycin Hydrochloride |
859-18-7 |
1g |
￥26400 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCL466200 |
リンコマイシン塩酸塩
Lincomycin Hydrochloride |
859-18-7 |
25g |
￥119400 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MPB02158948 |
リンコマイシン塩酸塩
Lincomycin Hydrochloride |
859-18-7 |
1g |
￥12300 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TRCL466200 |
リンコマイシン塩酸塩
Lincomycin Hydrochloride |
859-18-7 |
2g |
￥29700 |
2023-06-01 |
購入 |
リンコシン塩酸塩 化学特性,用途語,生産方法
化学的特性
Crystalline
使用
Lincomycin hydrochloride is a salt of lincomycin formed at the basic N-methylproline. The hydrochloride salt is the preferred formulation for pharmaceutical use. Lincomycin hydrochloride is a broad spectrum antibiotic with activity against anaerobic bacteria and protozoans. Lincomycin acts by binding to the 23S ribosomal subunit, blocking protein synthesis. Lincomycin has been extensively studied with over 7,000 literature citations.
一般的な説明
Chemical structure: macrolide
臨床応用
Lincomycin is used for the treatment of infections causedby Gram-positive organisms, notably staphylococci, β-hemolyticstreptococci, and pneumococci. It is absorbed moderatelywell orally and distributed widely in the tissues.Effective concentrations are achieved in bone for the treatmentof staphylococcal osteomyelitis but not in the cerebrospinalfluid for the treatment of meningitis. At one time,lincomycin was considered a nontoxic compound, with alow incidence of allergy (rash) and occasional GI complaints(nausea, vomiting, and diarrhea) as the only adverseeffects. Recent reports of severe diarrhea and the developmentof pseudomembranous colitis in patients treated withlincomycin (or clindamycin), however, have necessitatedreappraisal of the role of these antibiotics in therapy. In anyevent, clindamycin is superior to lincomycin for thetreatment of most infections for which these antibiotics areindicated.
Lincomycin hydrochloride occurs as the monohydrate, awhite, crystalline solid that is stable in the dry state. It isreadily soluble in water and alcohol, and its aqueous solutionsare stable at room temperature. It is degraded slowlyin acid solutions but is absorbed well from the GI tract.Lincomycin diffuses well into peritoneal and pleural fluidsand into bone. It is excreted in the urine and the bile. It isavailable in capsule form for oral administration and inampules and vials for parenteral administration.
リンコシン塩酸塩 上流と下流の製品情報
原材料
準備製品
リンコシン塩酸塩 生産企業
Global( 564)Suppliers
リンコシン塩酸塩 スペクトルデータ(IR1、MS)
859-18-7(リンコシン塩酸塩)キーワード:
- 859-18-7
- LINCOMYCIN HYDROCHLORIDE
- LINCOCIN HYDROCHLORIDE
- lincomycin standard solution
- ALPHA-METHYL-6,8-DIDEOXY-6-[1-METHYL-4-PROPYL-2-PYRROLIDINECARBOXAMIDO]-1-THIO-D-ERYTHRO-D-GALACTOOCTOPYRANOSIDE HYDROCHLORIDE
- U-10149A
- N-[2-HYDROXY-1-(3,4,5-TRIHYDROXY-6-METHYLSULFANYL-OXAN-2-YL)-PROPYL]-1-METHYL-4-PROPYL-PYRROLIDINE-2-CARBOXAMIDE
- D-erythro-.alpha.-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(2S,4R)-1-methyl-4-propyl-2-pyrrolidinylcarbonylamino-1-thio-, monohydrochloride
- lincomycin solution
- D-erythro-a-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[(1-methyl-4-propyl-2-pyrrolidinyl)carbonyl]amino]-1-thio-, monohydrochloride, (2S-trans)-
- D-erythro-a-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-, monohydrochloride (9CI)
- D-erythro-D-galacto-Octopyranoside, methyl 6,8-dideoxy-6-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-, monohydrochloride, trans-a- (8CI)
- Lincogap
- LINCOMYCINHYDROCHLORIDEANHYDROUS
- LINCOMYCIN CHLOROHYDRATE
- Lincocin
- Lincomycin hydrochloride BP98
- Methyl (2S-trans)-6,8-dideoxy-6-[[(1-methyl-4-propylpyrrolidin-2-yl)carbonyl]amino]-1-thio-D-erythro-alpha-D-galacto-octopyranoside monohydrochloride
- LINCOMYCIN HYDROCHLORIDE CELL CULTURE*TE STED
- Linocin, NSC 70731, U 10149a
- methyl 6,8-dideoxy-6-[[[(2S,4R)-1-methyl-4-propyl-2-pyrrolidinyl]carbonyl]amino]-1-thio-D-erythro-α-D-galacto-octopyranoside,hydrochloride (1:1)
- Lincoymcin Hcl
- Lincomycin hydrochloride (Lincocin)
- Lineomycin Hydrochloride
- Lincomycin (U-10149A)
- Lizpion
- Luniamycin
- Pelancocin
- Lincocin hydrochloride, Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride
- Methyl 6,8-dideoxy-6-trans-(1-methyl-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-D-erythro-alpha-D-galacto-octopyranoside hydrochloride
- Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride
- メチル6-[[[(2S,4R)-1-メチル-4-プロピル-2-ピロリジニル]カルボニル]アミノ]-6,8-ジデオキシ-1-チオ-D-erythro-α-D-galacto-オクトピラノシド·塩酸塩
- リンタマイシン
- 塩酸リンコマイシン
- ルニアマイシン
- リンコシン塩酸塩
- リンコメイス
- リンコマイシン塩酸塩
- リズピオン
- ペランコシン
- リンコマイシン塩酸塩標準品
- リンコマイシン塩酸塩一水和物標準品
- リンコマイシン 塩酸塩
- メチル6-[[[(2S,4R)-1-メチル-4-プロピル-2-ピロリジニル]カルボニル]アミノ]-6,8-ジデオキシ-1-チオ-D-erythro-α-D-galacto-オクトピラノシド・塩酸塩
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