TCS JNK 6o
TCS JNK 6o 物理性質
- 貯蔵温度 :
- Store at -20°C
- 溶解性:
- Soluble in DMSO
- 外見 :
- crystalline solid
- 色:
- White to off-white
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
TCS JNK 6o 価格
もっと(2)
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TOC3222 |
TCS JNK 6o |
894804-07-0 |
10mg |
¥82000 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01TOC3222 |
TCS JNK 6o |
894804-07-0 |
50mg |
¥348000 |
2024-03-01 |
購入 |
TCS JNK 6o 化学特性,用途語,生産方法
説明
c-
Jun amino terminal kinases (JNKs) are MAP kinase family members that become highly activated after cells are exposed to stress conditions and are poorly activated by exposure to growth factors or mitogens. They have been implicated in neurodegeneration, rheumatoid arthritis, inflammation, cancer, and diabetes. JNK1 and JNK2 are widely expressed throughout the body whereas JNK3 is predominantly distributed in the brain. JNK Inhibitor VIII is an aminopyridine compound that inhibits JNK1, JNK2, and JNK3 with K
i values of 2, 4, and 52 nM, respectively. It has been reported to inhibit the phosphorylation of the JNK substrate c-
Jun in HepG2 cells (EC
50 = 920 nM) without affecting the expression of IL-
6, IL-
8, or COX-
2.
使用
JNK Inhibitor VIII is an inhibitor shown to suppress apoptosis, caspase cleavage, and cytochrome C release.
TCS JNK 6o 上流と下流の製品情報
原材料
準備製品
TCS JNK 6o 生産企業
Global( 47)Suppliers
- 894804-07-0
- TCS JNK 6o
- JNK Inhibitor VIII
- N-(4-amino-5-cyano-6-ethoxypyridin-2-yl)-2-(2,5-dimethoxyphenyl)acetamide
- JNK INHIBITOR VIII (TCS JNK 6O)
- N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide
- JNK inhibitor VIII - JNK inhibitor compound 6o
- Benzeneacetamide, N-(4-amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxy-
- TCS JNK 6o(JNK Inhibitor VIII)
- JNK,inhibit,Inhibitor,JNK Inhibitor VIII