1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester

 化学構造式
21881-78-7
CAS番号.
21881-78-7
化学名:
别名:
英語名:
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester
英語别名:
Nimodipine EP Imp B;Nimodipine Impurity 2;Nilvadipine Impurity D;Nilvadipine Impurity 4;Nitrendipine Impurity 8;Nimodipine EP Impurity B;Nitrendipine Impurity1224;Nimodipine Impurity B Control;Bis(1-methylethyl) 2,6-Dimethyl-4-(;Nimodipine EP Impurity B(Nitrendipine Impurity1224)
CBNumber:
CB82717263
化学式:
C21H26N2O6
分子量:
402.44
MOL File:
21881-78-7.mol

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester 物理性質

融点 :
123-125℃ (ethanol )
沸点 :
512.1±50.0 °C(Predicted)
比重(密度) :
1.186±0.06 g/cm3(Predicted)
貯蔵温度 :
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解性:
クロロホルム(微量)、メタノール(微量)
外見 :
個体
酸解離定数(Pka):
2.94±0.70(Predicted)
色:
ペールベージュ
安定性::
Hygroscopic

安全性情報

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester 化学特性,用途語,生産方法

使用

3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine (Nimodipine EP Impurity B) can be used in synthetic preparation of dihydropyridinedicarboxylic acid esters by methylimidazolium trifluoroacetate-catalyzed Hantzsch cyclocondensation reaction of oxo-carboxylic acid esters with aldehydes and ammonium acetate. It can also be used as an analyte for analytical study in developing and optimizing a validated isocratic reversed-phase high-performance liquid chromatograhy separation of nimodipine and impurities in tablets using experimental. design methodology. It is an impurity of the drug Nimodipine (N478200).

1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester 上流と下流の製品情報

原材料

準備製品


1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester 生産企業

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21881-78-7()キーワード:


  • 21881-78-7
  • 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid bis(1-methylethyl) ester
  • Nimodipine EP Impurity B
  • (RS)-Di-iso-propyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate
  • Bis(1-methylethyl) 2,6-Dimethyl-4-(
  • Nimodipine Impurity B Control
  • 3,5-diisopropyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate
  • Nimodipine EP Imp B
  • Nimodipine Impurity 2
  • 3-Des(2-methoxyethyl) 3-(1-Methylethyl) Ester Nimodipine
  • Bis(1-methylethyl) 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Nitrendipine Impurity1224
  • diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
  • Nitrendipine Impurity 8
  • 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3,5-bis(1-methylethyl) ester
  • Nilvadipine Impurity D
  • Diisopropyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate (Nimodipine Impurity)
  • Nimodipine EP Impurity B(Nitrendipine Impurity1224)
  • Nilvadipine Impurity 4
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