1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
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- CAS番号.
- 1228780-72-0
- 化学名:
- 别名:
- 英語名:
- 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
- 英語别名:
- Abt199 int3;Venetoclax Intermediate 1;1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl...;1-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazine;1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine;(4-(2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine;1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]Piperazine;Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-;"1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1- en-1-yl]methyl}piperazine" ;1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methy)piperazine
- CBNumber:
- CB82742388
- 化学式:
- C19H27ClN2
- 分子量:
- 318.88
- MOL File:
- 1228780-72-0.mol
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1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 物理性質
- 沸点 :
- 421.2±45.0 °C(Predicted)
- 比重(密度) :
- 1.072±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- under inert gas (nitrogen or Argon) at 2–8 °C
- 酸解離定数(Pka):
- 9.21±0.10(Predicted)
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
絵表示(GHS) |
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注意喚起語 |
警告 |
危険有害性情報 |
コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
![](/GHS07.jpg) |
P264, P270, P301+P312, P330, P501 |
H315 |
皮膚刺激 |
皮膚腐食性/刺激性 |
2 |
警告 |
![](/GHS07.jpg) |
P264, P280, P302+P352, P321,P332+P313, P362 |
H319 |
強い眼刺激 |
眼に対する重篤な損傷性/眼刺激 性 |
2A |
警告 |
![](/GHS07.jpg) |
P264, P280, P305+P351+P338,P337+P313P |
H335 |
呼吸器への刺激のおそれ |
特定標的臓器毒性、単回暴露; 気道刺激性 |
3 |
警告 |
![](/GHS07.jpg) |
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|
注意書き |
P261 |
粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。 |
P305+P351+P338 |
眼に入った場合:水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
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1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 価格
もっと(8)
メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
富士フイルム和光純薬株式会社(wako)
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W01COBQE-9973 |
1-([2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl)piperazine dihydrochloride salt |
1228780-72-0 |
25g |
¥47500 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
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W01COBQE-9973 |
1-([2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl)piperazine dihydrochloride salt |
1228780-72-0 |
10g |
¥44600 |
2023-06-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
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W01COBQE-9973 |
1-([2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl)piperazine dihydrochloride salt |
1228780-72-0 |
1g |
¥10000 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01COBQE-9973 |
1-([2-(4-Chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl)piperazine dihydrochloride salt |
1228780-72-0 |
5g |
¥16500 |
2024-03-01 |
購入 |
富士フイルム和光純薬株式会社(wako)
|
W01FLC504674 |
1-([2-(4-CHLOROPHENYL)-4,4-DIMETHYLCYCLOHEX-1-EN-1-YL]METHYL)PIPERAZINE 2HCL SALT |
1228780-72-0 |
25g |
¥87800 |
2018-12-26 |
購入 |
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 化学特性,用途語,生産方法
使用
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine is an intermediate of Venetoclax (ABT-199) which is a small, oral chemical molecule used for the treatment of chronic lymphocytic leukemia (CLL) associated with a specific chromosomal abnormality.
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 上流と下流の製品情報
原材料
Methyl 2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-ene-1-carboxylate
4,4-ジメチル-2-オキソシクロヘキサンカルボン酸メチル
3,3-ジメチルシクロヘキサノン
(2-(4-クロロフェニル)-4,4-ジメチルシクロヘキス-1-エニル)メタノール
2-クロロ-4,4-ジメチルシクロヘキス-1-エンカルブアルデヒド
tert-butyl 4-((4'-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)Methyl)piperazine-1-carboxylate
Methyl 4,4-dimethyl-2-[(trifluoromethylsulfonyl)oxy]cyclohex-1-ene-1-carboxylate
4'-chloro-5,5-diMethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-carbaldehyde
2-(4-クロロフェニル)-4,4,5,5-テトラメチル-1,3,2-ジオキサボロラン
ピペラジン
4-クロロフェニルボロン酸
4-クロロヨードベンゼン
準備製品
1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine 生産企業
Global( 187)Suppliers
1228780-72-0()キーワード:
- 1228780-72-0
- 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine
- 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine dihydrochloride salt
- 1-((2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine
- Abt199 int3
- 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]Piperazine
- "1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1- en-1-yl]methyl}piperazine"
- 1-((4'-Chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methy)piperazine
- Piperazine, 1-[[2-(4-chlorophenyl)-4,4-dimethyl-1-cyclohexen-1-yl]methyl]-
- 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl...
- 1-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazine
- Venetoclax Intermediate 1
- (4-(2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-enyl)methyl)piperazine
- 1-((4'-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazine