ANTI-TAP
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
HPA061593 |
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
Anti-NXF1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution |
|
100μL |
￥89800 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
AV40639 |
IgG fraction of antiserum
Anti-NXF1 antibody produced in rabbit IgG fraction of antiserum |
|
100μL |
￥47900 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
AV40638 |
affinity isolated antibody
Anti-NXF1 antibody produced in rabbit affinity isolated antibody |
|
100μL |
￥102000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
HPA061593 |
Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
Anti-NXF1 antibody produced in rabbit Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution |
|
25μL |
￥33900 |
2023-06-01 |
購入 |
|
Sigma-Aldrich Japan
|
AV40639 |
IgG fraction of antiserum
Anti-NXF1 antibody produced in rabbit IgG fraction of antiserum |
|
100ul |
￥58600 |
2018-12-25 |
購入 |
ANTI-TAP 化学特性,用途語,生産方法
使用
Anti-NXF1 polyclonal antibody is used to tag nuclear RNA export factor 1 protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of nuclear RNA export factor 1 in polyA-RNA nuclear export.
一般的な説明
Nuclear RNA export factor 1 (NXF1, TAP) is a nuclear RNA exporter protein that contains a noncanonical RNP-type RNA binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. Nuclear RNA export factor 1 exports poly(A)+RNA from the nucleus into the cytoplasm.
Biochem/physiol Actions
NXF1 is one member of a family of nuclear RNA export factor. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF1 shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. NXF1 overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses.
ANTI-TAP 上流と下流の製品情報
原材料
準備製品
ANTI-TAP 生産企業
Global( 9)Suppliers
- ANTI-TAP
- ANTI-TRANSPORTER ASSOCIATED PROTEIN
- ANTI-TRANSPORTER ASSOCIATED WITH ANTIGEN PROCESSING
- Anti-DKFZp667O0311
- Anti-MEX67
- Anti-Nuclear RNA export factor 1
- Anti-NXF1 antibody produced in rabbit
- Anti-VDP P115 antibody produced in goat
- Anti-Vesicle docking protein