モノクローナル抗Β-チューブリン抗体-CY3標識 マウス宿主抗体 化学特性,用途語,生産方法
使用
Monoclonal Anti-β-Tubulin-Cy3 antibody produced in mouse has been used in:
- immunohistochemical assays
- immunofluorescence
- western blotting
- immunocytochemistry
- immunoblotting
- immunostaining
一般的な説明
β-Tubulin belongs to the subfamily of tubulins. It has two β-sheets enclosed by α-helices. It also contains an
N-terminal domain with the guanine nucleotide-binding region, an intermediate domain with taxol-binding site and a C-terminal domain, which has the binding surface for molecular motor proteins. Human β-tubulin consists of seven isoforms (βI (class I), βII (class II), βIII (class III), βIVa (class IVa), βIVb (class IVb), βV (class V), and βVI (class VI)). TUBB1 (tubulin beta class I) is located on human chromosome 6p21.33.(10)
Biochem/physiol Actions
Microtubules function as structural and mobile elements in mitosis, intracellular transport, flagellar movement and in the cytoskeleton. Mutation in the β-tubulin gene leads to various neuronal migration disorders such as lissencephaly, pachygyria and polymicrogyria malformations.
モノクローナル抗Β-チューブリン抗体-CY3標識 マウス宿主抗体 上流と下流の製品情報
原材料
準備製品