モノクローナル抗SNX4抗体 マウス宿主抗体 化学特性,用途語,生産方法
使用
Monoclonal Anti-SNX4 antibody produced in mouse may be used in:
- immunoblotting
- immunocytochemistry
- enzyme-linked immunosorbent assay (ELISA)
一般的な説明
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. (provided by RefSeq)
Biochem/physiol Actions
Sorting Nexins 4 (SNX4) protein interacts with various tyrosine kinase receptors. SNX4 protein and amphiphysin 2 interact in the cell cytosol and on cytoplasmic vesicular structures. Overexpression of the SNX4 gene blocks the endocytosis of the transferrin receptor as efficiently as amphiphysin 2. The SNX4/amphiphysin 2 complex is essential for the control of the endosome fate after the formation of the endocytic vesicle.
モノクローナル抗SNX4抗体 マウス宿主抗体 上流と下流の製品情報
原材料
準備製品