トランスフェリン 化学特性,用途語,生産方法
性質
Fe 輸送体．幼若赤血球のヘモグロビン合成にも必要．Tyr, Arg, His, AspなどでFeを結合
解説
鉄を結合して運搬する血清タンパク質．糖タンパク質の一種．鉄結合性グロブリン，シデロフィリンともいう．
天然物の起源
ヒト血漿：20～698ウシ血漿：20～704
使用
Transferrin, similar to insulin, is a component of most serum-free media formulations. The main function of transferrin is to transport iron into cells by receptor-mediated endocytosis.
Transferrin from human serum has been used as a supplement in:
- differentiation medium
- keratinocyte medium
- haemogenic endothelium culture medium
- embryoid-body medium
- blast colony forming cell-culture medium
一般的な説明
Transferrin is a serum glycoprotein that participates in the transport of iron from absorption and storage sites to tissue cells. The iron-bound transferrin, also referred to as ferrotransferrin, binds to specific cell surface receptors on growing cells and are internalized by endocytosis. Once inside, the iron is released into the cells and the iron-free transferrin, also referred to as apotransferrin, is exocytosed outside the cell without being degraded.
トランスフェリン 上流と下流の製品情報
原材料
準備製品