1-bromo-4-methyl-2-Pentanone

1-bromo-4-methyl-2-Pentanone 価格

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1-bromo-4-methyl-2-Pentanone 化学特性,用途語,生産方法

製造方法

Sytheisis of 1-Bromo-4-methylpentan-2-one: 4-Methylpentene (10.1 g, 120.0 mmmol) was mixed with water (500 mL) at 0 °C. Br2 (19.2 g, 120.0 mmol) was added dropwise and the mixture was stirred overnight at r.t. The mixture was extracted with pet. ether (4 x 75 mL). The organic phase was dried with MgSO4 and the solvent was evaporated under reduced pressure giving the crude product (19.15 g, brown oil). The crude product contained a mixture of 1,2 dibromo-4-methylpentane and 1-bromo-4- methylpentan-2-ol and 2-bromo-4-methylpentanol. The crude product was separated on DFC using the eluent (10% EtOAc in Hexanes) giving 1,2 dibromo-4-methylpentane (11.3 g) and a mixture of 1-bromo-4-methylpentan-2-ol and 2-bromo-4-methylpentanol (1.9 g). Chromic acid solution (12.3 mL) was added to the mixture of 1bromo-4-methylpentan-2-ol and 2- bromo-4-methylpentanol (1. 9 g) was dissolved in diethyl ether (50 mL) and the mixture was stirred overnight at r.t. Saturated NaHCO3 (aq) (200 mL) was added and the mixture was extracted with pet. ether (4 x 75 mL). The organic phase was dried with MgSO4 and the solvent was evaporated under reduced pressure giving the 1-bromo-4-methylpentan-2-one (0.72 g, brown oil, 3.3 %). The yield of this reaction was poor, but the same reaction is reported in 28% yield.

Chromic acid solution was prepared (500 mL):
Na2Cr2O7 x H2O (100 g, 0.33 mol) was dissolved in 300 mL of water. 97 % H2SO4 (136 g, 1. 34 mol) was then added. The solution was then diluted to 500 mL total volume. This solution will oxidize 1.00 mol of secondary alcohol.
Rf = 0.44 (15% EtOAc in Hexanes)

1-bromo-4-methyl-2-Pentanone 上流と下流の製品情報

原材料

準備製品

1-bromo-4-methyl-2-Pentanone 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shanghai Carlow Chemicals Co., Ltd.	21-33526724 18930996265	info@carlowchem.com	China	1807	50
Sanover (Xiamen) Technology Co., Ltd	059265188632; 13876246362	422165847@qq.com	China	501	58
Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd	18072846723	caigou1@witofly.com	China	18924	58

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• 29585-02-2
• 1-bromo-4-methyl-2-Pentanone
• 1-Bromo-4-methylpentan-2-one
• 2-Pentanone, 1-bromo-4-methyl-