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2-fdck / 2-fluorodeschloroketamine

化学構造式
111982-50-4
CAS番号.
111982-50-4
化学名:
别名:
英語名:
2-fdck / 2-fluorodeschloroketamine
英語别名:
2-Fluorodeschloroketamine;fdck;Fluorodeschloroketamine;2-FDCK;2fdck powder;2fdck crystal;2FDCK supplier;2f-dck white powder;2fdck, wickr: chemkitty;High purity 2-FDCK 2-FDCK
CBNumber:
CB93312820
化学式:
C13H16FNO
分子量:
221.27
MOL File:
111982-50-4.mol

2-fdck / 2-fluorodeschloroketamine 物理性質

沸点 :
333.6±42.0 °C(Predicted)
比重(密度) :
1.12±0.1 g/cm3(Predicted)
酸解離定数(Pka):
6.51±0.20(Predicted)

安全性情報

2-fdck / 2-fluorodeschloroketamine 化学特性,用途語,生産方法

来歴

The synthesis of 2-FDCK was first described in a 2013 paper as part of a larger effort to synthesize and evaluate new anesthetic drugs based on ketamine and its analogues. Ketamine itself was first introduced in 1964 and was approved for clinical use in 1970. Since then it has become one of the most important and applicable general anesthetics as well as a popular recreational drug.
The use of 2-FDCK as a designer drug has been reported in various countries. Many of these new psychoactive substances (NPS) appear on the drug market in order to circumvent existing drug policies. 2-FDCK was first formally notified by the EMCDDA in 2016, alongside 65 other new substances. Due to its recent appearance, little research has been done on the compound so far.

使用

2-(2-Fluorophenyl)-2-(methylamino)-cyclohexanone is a related compound of Ketamine (K165300), an anesthetic.

薬物動態学

2-FDCK is structurally similar to ketamine, so a similar mechanism of action is expected, but there has been no study done to confirm this. Due to the halogen in the 2 position not being a chlorine but a fluorine, the molecule is less polar. This could influence binding to proteins, such as the NMDA receptor that ketamine primarily binds to and acts as an antagonist towards.

2-fdck / 2-fluorodeschloroketamine 上流と下流の製品情報

原材料

Cyclopentanol, 1-[(2-fluorophenyl)(methylimino)methyl]- (1-Bromocyclopentyl)(2-fluorophenyl)methanone 2-フルオロフェニルシクロペンチルケトン 2-フルオロベンゾニトリル

準備製品

111982-50-4()キーワード:

メチル2-{[1-(シクロヘキシルメチル)インドール-3-イル]ホルムアミド}-3-メチルブタノアート 5F-ADB 6-(2-アミノプロピル)ベンゾフラン
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