N'-(3-acetamidophenyl)-N-[2-[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]ethyl]oxamide 化学特性,用途語,生産方法
説明
S1QEL1.1 is a small molecule that suppresses superoxide production during reverse electron transport through the I
Q site of the mitochondrial respiratory complex I (IC
50 = 70 nM) without affecting oxidative phosphorylation. It diminishes endogenous oxidative damage in primary astrocytes, reduces stress-induced signaling in a cardiomyocyte cell model, and protects against ischemia-reperfusion injury in perfused mouse heart.
N'-(3-acetamidophenyl)-N-[2-[4-methyl-2-(4-methylphenyl)-1,3-thiazol-5-yl]ethyl]oxamide 上流と下流の製品情報
原材料
準備製品