モノクローナル抗神経成長因子-Β抗体 マウス宿主抗体 化学特性,用途語,生産方法
使用
Anti-NGF-β antibody may be used for neutralization assays; the ND50 is ~0.02-0.1 μg/ml. For immunoblotting the recommended antibody concentration is 0.1-0.2 μg/ml. The antibody is suitable for immunohistochemistry at a working concentration of 5-15 μg/ml. For ELISA, antibody concentration of 0.2-0.8 μg/ml may be used. Antibody dilution of 1:500 was used for immunoblotting of extracts of rat nerve cells.
一般的な説明
Nerve Growth factor (NGF) is a growth factor that is essential for the development and maintenance of the nervous system. NGF is composed of three non-covalently linked α, β and γ subunits. The β subunit is responsible for the biological functions of NGF. Nerve growth factor (NGF) binds to either to NGF receptor (NGFR) or the Trk receptor and can elicit biological responses through each of the receptors independently. NGF is important in the survival and differentiation of neurons and neural crest-derived cells during embryonic and early postnatal development and maintenance of peripheral neurons. NGF is also implicated in inflammation and allergic reactions . Anti-Nerve Growth Factor-β antibody recognizes rat NGF-β. The antibody shows less than 1% cross reactivity with recombinant human β-NGF.
Biochem/physiol Actions
Nerve Growth factor (NGF) is a growth factor that is essential for the development and maintenance of the nervous system. NGF is composed of three non-covalently linked α, β and γ subunits. The β subunit is responsible for the biological functions of NGF. Nerve growth factor (NGF) binds to either to NGF receptor (NGFR) or the Trk receptor and can elicit biological responses through each of the receptors independently. NGF is important in the survival and differentiation of neurons and neural crest-derived cells during embryonic and early postnatal development and maintenance of peripheral neurons. NGF is also implicated in inflammation and allergic reactions.
モノクローナル抗神経成長因子-Β抗体 マウス宿主抗体 上流と下流の製品情報
原材料
準備製品