1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩
1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩 物理性質
- 融点 :
- 230°C
- 外見 :
- solid
- 色:
- White
安全性情報
1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩 価格
もっと(11)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-6022 |
1-[(Ammoniooxy)methyl]-4-chlorobenzene chloride |
38936-60-6 |
10g |
￥245000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-6022 |
1-[(Ammoniooxy)methyl]-4-chlorobenzene chloride |
38936-60-6 |
25g |
￥490000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01APOOR6060 |
O-(4-クロロベンジル)ヒドロキシルアミン塩酸塩
O-(4-Chlorobenzyl)hydroxylamine hydrochloride |
38936-60-6 |
1g |
￥55200 |
2023-06-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01APOOR6060 |
O-(4-クロロベンジル)ヒドロキシルアミン塩酸塩
O-(4-Chlorobenzyl)hydroxylamine hydrochloride |
38936-60-6 |
5g |
￥211200 |
2023-06-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS044741 |
1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩
1-[(Aminooxy)methyl]-4-chlorobenzene hydrochloride |
38936-60-6 |
500mg |
￥23500 |
2024-03-01 |
購入 |
1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩 化学特性,用途語,生産方法
製造方法
To a solution of 83.7 gm (1.5 moles) of potassium hydroxide in 560 ml of water is added in turn with stirring, 300 gm (0.985 mole) of dipotassium hydroxylaminedisulfonate and 161 gm (1.0 mole) of 4-chlorobenzyl chloride. The stirred mixture is heated on a steam bath for 1.75 hr. After cooling, the precipitate is filtered off and refluxed for 3 hr in 1000 ml of 1.5 Ν sulfuric acid. The reaction mixture is then cooled and made strongly alkaline with a 15% aqueous sodium hydroxide solution. The mixture is then extracted with ether repeatedly. The ether extracts are combined and evaporated to dryness. The solid residue (crude free base, 80 gm, i.e., 51.5% of theory, m.p. 35-38°C) is taken up in 1 liter of ether. Anhydrous hydrogen chloride is bubbled through this solution to precipitate the hydrochloride salt. The yield is 59 gm (31%, overall), m.p. 243-244°C (dec); the free base has b.p. 100°C/1 mm Hg. In this preparation, the hydrolysis of the alkylated dipotassium hydroxylaminedisulfonate with only 1 liter of 1.5 Ν sulfuric acid seems somewhat skimpy. We suggest that a higher level of sulfuric acid be considered at that stage of the reaction, if the alkylation has indeed gone to completion. Once the O-alkylhydroxylamine has been prepared by this reaction, it may be N-alkylated to produce an N,Ο-dialkylhydroxylamine.
The preparation of O-phenylhydroxylamine has been a synthetic challenge for some time since it is quite unstable. Using hydroxylamine-O-sulfonic acid. A small quantity of this compound has been prepared [36]. Reaction conditions probably require further study to improve the yield. Extension of the reaction to the preparation of O-alkylhydroxylamines would be of interest.
1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩 上流と下流の製品情報
原材料
準備製品
1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩 生産企業
Global( 60)Suppliers
38936-60-6(1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩)キーワード:
- 38936-60-6
- o-(p-chlorobenzyl)-hydroxylaminhydrochloride
- O-(4-CHLOROBENZYL)HYDROXYLAMINE HYDROCHLORIDE
- 1-[(AMINOOXY)METHYL]-4-CHLOROBENZENE HYDROCHLORIDE
- 1-[(AMMONIOOXY)METHYL]-4-CHLOROBENZENE CHLORIDE
- O-(4-chlorobenzyl) hydroxylaMine
- 4-Chlorobenzyloxyamine hydrochloride
- O-(4-Chlorobenzyl)hydroxylamine hydrochloride
4-Chlorobenzyloxyamine hydrochloride
- O-[(4-chlorophenyl)methyl]Hydroxylamine hydrochloride
- Hydroxylamine, O-[(4-chlorophenyl)methyl]-, hydrochloride (1:1)
- O-(p-Chlorobenzyl)hydroxylamine hydrochloride
- 1-[(aminooxy)methyl]-4-chlorobenzene hydrochloride (1:1)
- O-(4-CHLOROBENZYL)HYDROXYLAMINE HCL
- 1-[(アミノオキシ)メチル]-4-クロロベンゼン塩酸塩
- 1-[(アンモニオオキシ)メチル]-4-クロロベンゼンクロリド
- O-(4-クロロベンジル)ヒドロキシルアミン塩酸塩
- O-[(4-クロロフェニル)メチル]ヒドロキシルアミン・塩酸塩