10-DEBC HYDROCHLORIDE 化学特性,用途語,生産方法
生物活性
Selective inhibitor of Akt/PKB. Inhibits IGF-1-stimulated phosphorylation and activation of Akt (complete inhibition at 2.5 μ M), suppressing downstream activation of mTOR, p70 S6 kinase and S6 ribosomal protein. Shows no activity at PDK1, SGK1 or PI 3-kinase. Inhibits cell growth (IC 50 ~ 2-6 μ M) and induces apoptosis in rhabdomyosarcoma cells.
10-DEBC HYDROCHLORIDE 上流と下流の製品情報
原材料
準備製品