2-クロロプロパン 化学特性,用途語,生産方法
外観
無色～ほとんど無色, 澄明の液体
溶解性
水に不溶, アルコール, エーテル等各種有機溶剤と混和。エタノール及びアセトンに極めて溶けやすく、水にほとんど溶けない。
用途
溶媒、農薬など化学製品の中間体。
用途
有機合成原料。
化学的特性
Colourless liquid
使用
2-Chloropropane decomposes by first-order reaction to give hydrogen chloride and propylene. It is a short-chain chlorinated paraffins that is a component in lubricant additives, metal processing, leather fat-liquoring, plastics softening, PVC plasticizing, flame retardants in paints, adhesives and sealants. It shows anesthetic properties. Further, it is used as an alternative foam-blowing agent.
2-Chloropropane is used as a solvent and an intermediate.It can be used as a reactant:
In the Friedel-Crafts alkylation reaction of difluorobenzene and toluene using solid acid and methylalumoxane catalysts, respectively.
To prepare 4-amino-3-iodo-1-(isopropyl)pyrazolo[3,4-d]pyrimidine, a key intermediate for the synthesis of PfPK7 kinase inhibitors.
It is used to prepare benzylisopropylphenylphosphine and chlorodiethylisopropylsilane.
一般的な説明
A colorless liquid with a chloroform-like odor. Vapors heavier than air. Less dense than water. May irritate skin and eyes, and be narcotic in high concentrations. A fire and explosion risk. Used to make other chemicals.
空気と水の反応
Highly flammable. Slightly soluble in water.
反応プロフィール
Halogenated aliphatic compounds, such as 2-Chloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.
危険性
Highly flammable, fire and explosion risk,
explosive limits in air 2.8–10.7%.
健康ハザード
ACUTE/CHRONIC HAZARDS: Fire hazard: Highly dangerous; when exposed to heat, flame or oxidizers. Explosion hazard: Moderate when exposed to heat or flame.
火災危険
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.
安全性プロファイル
Mutation data reported.
A flammable liquid. A very dangerous fire
hazard when exposed to heat, flame, or
oxidners. When heated to decomposition it
emits toxic fumes of Cl-. See also 1
CHLOROPROPANE.
純化方法
Purify the chloride with 95% H2SO4 as described for isopropyl bromide, then dry with MgSO4, P2O5 or CaH2, and fractionally distil it from Na2CO3 or CaH2. Alternatively, a stream of oxygen containing ca 5% ozone is passed through the chloride for about three times as long as is necessary to obtain the first coloration of starch iodide paper by the exit gas, and the liquid is then washed with NaHCO3 solution to hydrolyse ozonides and remove organic acids before drying and distilling. [Beilstein 1 IV 191.]
2-クロロプロパン 上流と下流の製品情報
原材料
準備製品