4-브로모부틸질산염
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4-브로모부틸질산염 속성
- 끓는 점
- 220.0±23.0 °C(Predicted)
- 밀도
- 1.560±0.06 g/cm3(Predicted)
- 저장 조건
- Refrigerator, under inert atmosphere
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 기름
- 색상
- 옅은 노랑
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
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| 신호 어: | Warning | ||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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4-브로모부틸질산염 C화학적 특성, 용도, 생산
용도
4-bromobutyl nitrate is an intermediate in synthesizing Latanoprostene Bunod (L177335). It is a derivative of Latanoprost and is used in the treatment of interocular pressure.제조 방법
4-Bromobutyl nitrate is a thermally unstable oily liquid, which is used to obtain nitrooxyalkyl esters of pharmacologically active carboxylic acids (WO 04/020384, WO 04/020385). 4-Bromobutyl nitrate not dissolved in solvents is added to the solution / suspension of pharmacologically active carboxylic acids such as naproxen, ferulic acid, etc. 4-Bromobutyl nitrate is obtained by nitration with a sulfonitizing mixture of 4-bromo-1-hydroxybutane (Chem. Pharm. Bull., 1993, 41, p. 1040). The reaction is carried out by adding 4-bromo-1-hydroxybutane to the crude sulphonating mixture in the absence of solvents or diluents. The reaction is limited to a laboratory scale since the method is potentially explosive due to a sudden increase in temperature and gas production.https://patents.google.com/patent/RU2388746C2/en
4-브로모부틸질산염 준비 용품 및 원자재
원자재
준비 용품
4-브로모부틸질산염 공급 업체
글로벌( 9)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 |
cbc@coresyn.com | China | 9984 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29793 | 60 |
| Suzhou Rovathin Foreign Trade Co.,Ltd | 0512-65816829 18662214788 |
info@rovathin.com.cn | China | 9663 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 4008210725 4008210725 |
malulu@leyan.com | China | 54987 | 58 |
| Ningbo jinuo chemical co., LTD | 0574-87314919 057487319282 |
info@nbinno.com | China | 7035 | 58 |
| Cato Research Chemicals Inc. | 020-81960175-877 18933936954 |
tianwen.zhan@cato-chem.com | China | 7735 | 58 |
| Suzhou Meishi Biotechnology Co., Ltd. | 1173954148q |
meishipharma@126.com | China | 20033 | 58 |
| Suzhou Haiben Pharmaceutical Co., Ltd | 14760821013 13564957716 |
1816280386@qq.com | China | 8045 | 58 |